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7,8,9- trihydroxy- 10- chloro- 7,8,9,10- tetrahydrobenzo(a)pyrene

structure given in first source

Also Known As:

trans-BPDCH

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Polycyclic Aromatic Hydrocarbons: 2020
        Pyrenes: 10
        Benzopyrenes: 67
        7,8,9-trihydroxy-10-chloro-7,8,9,10-tetrahydrobenzo(a)pyrene: 1
Polycyclic Compounds: 6
- Polycyclic Aromatic Hydrocarbons: 2020
  - Pyrenes: 10
    - Benzopyrenes: 67
      - 7,8,9-trihydroxy-10-chloro-7,8,9,10-tetrahydrobenzo(a)pyrene: 1

Experts

1.	Meehan, T: 1 article (07/2001)
2.	Vock, E H: 1 article (07/2001)
3.	Wolfe, A R: 1 article (07/2001)

Related Diseases

1.

Hypertension (High Blood Pressure)

07/01/2001 - "In order to achieve the same adduct concentration in mouse, spontaneous hypertension rat (SHR), and Sprague-Dawley (SD) rat skin, respectively, a 37-, 23- and 10-fold lower dose of anti-BPDE than of trans-BPDCH had to be applied. "
07/01/2001 - "Skin from C57Bl6 mice, spontaneous hypertension rats (SHR) and Sprague-Dawley (SD) rats was treated ex vivo immediately after the death of the animals with anti-BPDE and its corresponding bay region chlorohydrin trans-BPDCH and the epidermis was analyzed for DNA adducts 1h after the application. "

Related Drugs and Biologics

1.	DNA Adducts
2.	7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide