RS 66271

obtained by substituting a model amphipathic alpha-helical peptide (MAP) sequence in the C-terminal region of human parathyroid hormone-related protein (1-34); amino acid sequence given in first source

Also Known As:

(MAP 1-10)(22-31) hPTHrP(1-34)-NH2; RS-66271

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Hormones, Hormone Substitutes, and Hormone Antagonists
- Hormones: 80400
  - Peptide Hormones: 1347
    - Parathyroid Hormone: 11951
      - Teriparatide: 1461
        RS 66271: 2
Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Peptide Hormones: 1347
    - Parathyroid Hormone: 11951
      - Teriparatide: 1461
        RS 66271: 2

Related Diseases

1.	Osteoporosis 12/01/1996 - "The results suggest that RS-66271 may be a candidate molecule for the treatment of human osteoporosis."
2.	Bone Resorption 02/01/1999 - "Despite this reduced binding affinity, RS-66271 had equivalent activity in increasing both cAMP production in osteoblast-like cells and bone resorption in neonatal mouse calvariae. "