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N-(3-(aminomethyl)benzyl)acetamidine

structure in first source

Also Known As:

1400W cpd

Networked: 6 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133

Experts

1.	Durbin, Adam: 1 article (01/2005)
2.	Gotlieb, Avrum I: 1 article (01/2005)
3.	Nadir, Nur-Ain: 1 article (01/2005)
4.	Rosenthal, Alan: 1 article (01/2005)
5.	Kawanishi, Hiromi Nakano: 1 article (08/2004)
6.	Kawashima, Nobuyuki: 1 article (08/2004)
7.	Suda, Hideaki: 1 article (08/2004)
8.	Suzuki, Noriyuki: 1 article (08/2004)
9.	Takagi, Minoru: 1 article (08/2004)
10.	Fujii, Junichi: 1 article (06/2004)

Related Diseases

1.	Pulpitis 08/01/2004 - "This study aimed to evaluate the anti-inflammatory effects of an iNOS-specific inhibitor, N-(3-(aminomethyl)benzyl)acetamidine (1400W), on experimentally induced rat pulpitis in the upper incisors of 6-wk-old male Wistar rats. "
2.	Allergic Rhinitis 05/03/2002 - "The selective iNOS inhibitor N-(3-(aminomethyl)benzyl)acetamidine (1400 W, 0.1-1.0 mM) significantly reduced the chemotaxis of eosinophils from healthy but not from allergic rhinitis subjects. "
3.	Endotoxemia 06/01/2004 - "Thus, we elucidated in vivo cross talk between prostanoids and NO in gastric mucosa during endotoxemia, using an iNOS-specific inhibitor, N-(3-(aminomethyl)benzyl)acetamidine (1400W); a nonspecific COX inhibitor, indomethacin; and a COX-2-specific inhibitor, N-(2-[cyclohexyloxy]-4-nitrophenyl)methanesulfonamide (NS-398). "
4.	Wounds and Injuries (Trauma) 01/01/2005 - "Cultures were also incubated with iNOS inhibitors L-N(G)-nitroarginine methyl ester (L-NAME) and N-(3-(Aminomethyl)benzyl)acetamidine (1400W), and the extent of wound closure with and without inhibitor was measured at 24, 48 and 72 h postwounding. "
5.	Neoplasms (Cancer) 08/01/1997 - "We have investigated the effect of N-(3-(aminomethyl)benzyl)acetamidine (1400W), a novel and highly selective inhibitor for inducible NOS (iNOS), on in vivo growth of solid tumors expressing iNOS. "

Related Drugs and Biologics

1.	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)
2.	NG-Nitroarginine Methyl Ester (L-NAME)
3.	Prostaglandins
4.	Indomethacin (Indometacin)
5.	Acids
6.	N- ((3- (aminomethyl)phenyl)methyl)ethanimidamide
7.	methanesulfonamide