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BW 250 183

a Tc-99m-labeled antigranulocyte antibody; readily available and has high imaging quality; has a large molecular size - 150 kDa

Also Known As:

99Tcm-BW250-183; BW 25-183, Tc-99m-antigranulocyte antibody; BW 250-183; Tc-99m-AGAB BW 250-183; technetium-99m-antigranulocyte antibody BW 250-183

Networked: 24 relevant articles (0 outcomes, 1 trials/studies) for this Bio-Agent, Comments

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins
- Proteins: 60567
  - Blood Proteins: 3714
    - Serum Globulins: 71
      - Immunoglobulins: 19415
        Antibodies: 74529
        Monoclonal Antibodies: 16060
        BW 250 183: 24
    - Immunoproteins: 28
      - Immunoglobulins: 19415
        Antibodies: 74529
        Monoclonal Antibodies: 16060
        BW 250 183: 24
  - Globulins: 283
    - Serum Globulins: 71
      - Immunoglobulins: 19415
        Antibodies: 74529
        Monoclonal Antibodies: 16060
        BW 250 183: 24

Experts

1.	Müller, Peter Ernst: 1 article (08/2010)
2.	Lehner, Sebastian: 1 article (08/2010)
3.	Haug, Alexander: 1 article (08/2010)
4.	Hacker, Marcus: 1 article (08/2010)
5.	Graute, Vera: 1 article (08/2010)
6.	Feist, Markus: 1 article (08/2010)
7.	Bartenstein, Peter: 1 article (08/2010)
8.	Strosche, H: 1 article (01/2009)
9.	Reize, P: 1 article (01/2009)
10.	Kaiser, J W: 1 article (01/2009)

Related Diseases

1.	Inflammation 06/01/1992 - "It may be concluded that the detection of foci of inflammation with the 99mTc-labelled MAb BW 250/183 is of great diagnostic value and that its administration can be repeated without risk." 06/01/1992 - "[The detection of inflammation and the formation of HAMA following the administration of monoclonal antibody BW 250/183]" 04/01/1990 - "According to our experiences, immunoscintigraphy with 99mTc-MAb BW 250/183 has a sensitivity of 95%, and is, therefore, well suited for the identification of leukocytic inflammations." 01/01/2004 - "AIMS: The aim of our study was to investigate whether scintigraphy with (99m)Tc-Anti-Granulocyte BW 250/183 antibody is a valuable diagnostic method in evaluating focal and diffuse inflammation of the heart and could therefore be suggested for use in screening for acute myocarditis. " 01/01/1998 - "They contribute not only in tumor diagnostic where monoclonal antibodies against tumorous antigens (TAG 72, CEA) are used but also in the sphere of inflammation diagnostic with the use of monoclonal antibody BW 250/183 which is bound onto non-specific cross reacting antigen NCA 95 of granulocytes. " Order ALL the reference details at left...
2.	Myocarditis (Carditis) 01/01/2004 - "Screening for acute myocarditis--is scintigraphy with (99m)Tc-Anti-Granulocyte BW 250/183 an answer?" 01/01/2004 - "AIMS: The aim of our study was to investigate whether scintigraphy with (99m)Tc-Anti-Granulocyte BW 250/183 antibody is a valuable diagnostic method in evaluating focal and diffuse inflammation of the heart and could therefore be suggested for use in screening for acute myocarditis. " Order ALL the reference details at left...
3.	Infection 02/01/2002 - "A strong correlation could be demonstrated between T/NT ratios of infection and bloodpool Tc-99m medronate imaging (r = 0.84, 0.88) and between infection and BW 250/183 (r = 0.92, 0.90). " 09/01/1993 - "Detection of lung and bone infection with anti-granulocyte monoclonal antibody BW 250/183 radiolabelled with 99Tcm." 11/01/2003 - "Specificity and accuracy are lower than in the evaluation of hip prostheses; however, in comparison to other scintigraphic modalities, scintigraphy with the antigranulocyte antibody BW 250/183 is superior in excluding infection and has better specificity and accuracy. " 11/01/2003 - "Immunoscintigraphy with the use of the antigranulocyte antibody BW 250/183 is a reliable method for detecting infection, especially in septic loosening of hip prostheses, for which purpose quantitative interpretation of the time-activity course is employed. " 08/01/2010 - "METHODS: Planar scintigraphy using (99m)Tc-labelled antigranulocyte BW 250/183 antibodies was performed in 31 patients with suspected joint infections at 5 min, 5 h and 24 h after injection, with additional SPECT/CT performed 6 h after injection. " Order ALL the reference details at left...
4.	Neoplasms (Cancer) 02/01/1990 - "Until now the clinical identification of the affinity of monoclonal 99mTc-anti-CEA antibodies (MAK BW 250/183) on granulocytes was made with tumor cells carrying the same epitope on NCA-95 and human granulocytes in vitro. " 01/01/1998 - "They contribute not only in tumor diagnostic where monoclonal antibodies against tumorous antigens (TAG 72, CEA) are used but also in the sphere of inflammation diagnostic with the use of monoclonal antibody BW 250/183 which is bound onto non-specific cross reacting antigen NCA 95 of granulocytes. " Order ALL the reference details at left...
5.	Neoplasm Metastasis (Metastasis) 09/01/1990 - "Radioimmune imaging of bone marrow was performed by technetium-99m- (99mTc) labeled antigranulocyte monoclonal antibody BW 250/183 (AGMoAb) scans in 32 patients with suspected bone metastases from primary breast cancer. " 05/01/1997 - "Aghia Paraskevi, Attikil and Tc-99m Anti-Granulocyte BW 250/183 [CIS Bio International, Gif sur Yvette, France] bone scans were performed on 2 prostate cancer patients and 5 women with breast cancer with disseminated bone metastases. " Order ALL the reference details at left...

Related Drugs and Biologics

1.	Monoclonal Antibodies
2.	Antibodies
3.	Indium
4.	Antigens
5.	hexamethylpropyleneamine oxime

Related Therapies and Procedures

1.	Transplants (Transplant)
2.	Prostheses and Implants (Prosthesis)
3.	Hip Prosthesis
4.	Arthroplasty

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