mouse Dtx1 protein

FXI-T1 - fractionated X-irradiation-Induced Transcript 1, a homolog of Drosophila deltex protein; regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations; involved in neurogenesis, lymphogenesis and myogenesis, and may also be involved in MZB (Marginal zone B) cell differentiation; promotes B-cell development at the expense of T-cell development, suggesting that it may antagonize NOTCH1; amino acid sequence given in first source; GenBank U38252 and AB015422; RefSeq NM_008052
Also Known As:
Dtx1 protein, mouse; deltex protein 1, mouse
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