|1.||Zhang, Guang-Yi: 8 articles (01/2012 - 05/2005)|
|2.||Rana, Basabi: 4 articles (08/2015 - 02/2010)|
|3.||Sondarva, Gautam: 4 articles (08/2015 - 02/2010)|
|4.||Dewhurst, Stephen: 4 articles (01/2014 - 05/2010)|
|5.||Zhang, Quan-Guang: 4 articles (12/2006 - 05/2005)|
|6.||Rana, Ajay: 3 articles (08/2015 - 02/2010)|
|7.||Polesskaya, Oksana: 3 articles (01/2014 - 12/2010)|
|8.||Gelbard, Harris A: 3 articles (01/2014 - 12/2010)|
|9.||Chadee, Deborah N: 3 articles (04/2013 - 03/2006)|
|10.||Rangasamy, Velusamy: 3 articles (10/2011 - 02/2010)|
01/20/2012 - "Previous studies in our laboratory have shown that mixed lineage kinase 3 (MLK3) can be activated following global ischemia. "
12/01/2007 - "Our recent studies have shown that mixed-lineage kinase 3 (MLK3) and apoptosis-inducing kinase 1 (ASK1) are all involved in neuronal cell death induced by ischemia, which is mediated by the MLK3/c-Jun NH2-terminal kinase 3 (JNK3) and ASK1/JNK signaling pathway. "
09/01/2014 - "The phosphorylation and protein expression of Mixed lineage kinase 3 (MLK3) at ischemia/reperfusion (I/R) 6 h and c-Jun N-terminal kinase (JNK) at I/R 3 d were detected using immunoblotting analysis, respectively. "
12/01/2006 - "Our results showed that chronic pretreatment with beta-estradiol 3-benzoate (E2) enhanced Akt1 activation and reduced the activation of mixed-lineage kinase 3 (MLK3), mitogen-activated protein kinase kinase 4/7 (MKK4/7), and c-Jun N-terminal kinase 1/2 (JNK1/2) in the hippocampal CA1 subfield during reperfusion after 15 min of global ischemia. "
|2.||Brain Ischemia (Cerebral Ischemia)
01/20/2012 - "S-nitrosylation of mixed lineage kinase 3 contributes to its activation after cerebral ischemia."
09/01/2006 - "The overall goal of this study was to determine the molecular basis by which mixed-lineage kinase 3 (MLK3) kinase and its signaling pathways are negatively regulated by the pro-survival Akt pathway in cerebral ischemia. "
12/31/2005 - "N-Acetylcysteine inhibit the translocation of mixed lineage kinase-3 from cytosol to plasma membrane during transient brain ischemia in rat hippocampus."
12/01/2009 - "Our previous researches have shown that cerebral ischemia/reperfusion could facilitate the assembly of GluR6 and postsynaptic density protein 95(PSD95) as well as mixed lineage kinase 3(MLK3) and further induce the activation of c-Jun NH2-terminal kinase 3(JNK3), leading to neuronal death of hippocampal CA1. "
09/09/2008 - "Moreover, treatment with sodium nitroprusside (SNP), an exogenous NO donor, increases the S-nitrosylation and phosphorylation of nNOS, leading to the attenuation of the increased S-nitrosylation of GluR6 and the assembling of GluR6* postsynaptic density protein 95 (PSD95)* mixed lineage kinase 3 (MLK3) signaling module induced by cerebral ischemia-reperfusion. "
|3.||Stomach Neoplasms (Stomach Cancer)
01/01/2010 - "Further studies showed that mitogen-activated protein kinase kinase kinase 11 was significantly down-regulated by miR-199a at the post-transcriptional level and, the level of miR-199a expression in gastric cancer significantly correlated with clinical progression. "
01/01/2010 - "miR-199a regulates the tumor suppressor mitogen-activated protein kinase kinase kinase 11 in gastric cancer."
03/01/2010 - "Mixed lineage kinase-3/JNK1 axis promotes migration of human gastric cancer cells following gastrin stimulation."
|5.||Transient Ischemic Attack
08/28/2009 - "In our previous studies, Tat-GluR6-9c (a glutamate receptor 6 C-terminus peptide fused the TAT protein transduction sequence) not only inhibited the activation of MLK3 (mixed lineage kinase 3) and JNK (c-Jun N-terminal kinase) via the GluR6.PSD-95 (postsynaptic density protein 95).MLK3 signaling module but also diminished neuronal death induced by kainic acid or transient cerebral ischemia in rat hippocampus. "
|2.||postsynaptic density proteins
|3.||JNK Mitogen-Activated Protein Kinases
|4.||Glutamate Receptors (Glutamate Receptor)
|5.||tat Gene Products (tat Protein)
|6.||Kainic Acid (Kainate)
|7.||MAP Kinase Kinase 4
|9.||MAP Kinase Kinase Kinase 5
|10.||Mitogen-Activated Protein Kinase 8
|1.||Heterologous Transplantation (Xenotransplantation)