|1.||Izquierdo, Iñaki: 11 articles (03/2013 - 06/2003)|
|2.||Izquierdo, I: 9 articles (01/2013 - 01/2004)|
|3.||Mullol, J: 5 articles (01/2015 - 04/2008)|
|4.||Maurer, M: 4 articles (01/2015 - 04/2008)|
|5.||Valero, A: 4 articles (01/2011 - 07/2004)|
|6.||Solans, Anna: 4 articles (09/2008 - 01/2006)|
|7.||Merlos, Manuel: 4 articles (09/2008 - 06/2003)|
|8.||Palani, Anuradha: 3 articles (12/2011 - 08/2010)|
|9.||Maiti, Rituparna: 3 articles (12/2011 - 08/2010)|
|10.||Jaida, Jyothirmai: 3 articles (12/2011 - 08/2010)|
01/01/2007 - "Clinical trials show that rupatadine is an effective and generally well tolerated treatment for allergic rhinitis and CIU. "
04/01/2010 - "These positive results could explain the effectiveness of rupatadine in the treatment of persistent allergic rhinitis, as reported in a previous study Further controlled studies need to be conducted to confirm these preliminary findings."
01/01/2015 - "This study, which included a wide cohort of allergic-rhinitis patients, confirmed the clinical benefit of rupatadine when prescribed in clinical practice, even for the most severe symptoms, including nasal congestion."
01/01/2015 - "Rupatadine relieves allergic rhinitis: a prospective observational study."
11/01/2013 - "This systematic review was aimed at identifying in the most important databases, up to January 2013, the double-blind placebo-controlled randomized trials administering rupatadine in allergic rhinitis. "
09/01/2009 - "This responder analysis, using different response levels, shows that the efficacy of rupatadine 10 mg and 20 mg is significantly better as compared to placebo in the treatment of chronic urticaria patients. "
09/01/2013 - "However, further clinical trials to evaluate the efficacy of rupatadine in different urticaria subtypes and to test the safety of doses higher than 20 mg are encouraged."
09/01/2013 - "This study evaluates the effectiveness and safety of rupatadine in chronic urticaria (CU) and acquired cold urticaria (ACU), through a systematic review of the literature. "
09/01/2009 - "This analysis includes the pooled data from two randomized, double-blind, placebo-controlled, multicentre studies in which chronic urticaria patients were treated with rupatadine at different doses. "
09/01/2009 - "Two previous randomized clinical trials demonstrated rupatadine efficacy and safety in chronic urticaria treatment. "
01/01/2010 - "A significant reduction of critical temperature threshold (P < .001) and reduced scores for cold provocation-induced wheal reactions (P = .01), pruritus (P = .005), burning sensation (P = .03), and subjective complaints (P = .03) after rupatadine treatment were also found. "
05/01/2007 - "This randomized, double-blind, placebo-controlled, parallel-group, multicentre, study was designed to assess primarily mean pruritus score (MPS) reduction with rupatadine, 10 and 20 mg, administered once daily for 4 weeks. "
07/01/2012 - "The accompanying pruritus decreased from 60 (VAS; median) under placebo to 47.5 under rupatadine, which also is a significant (P=0.019) difference. "
05/01/2007 - "Rupatadine decreased pruritus severity, in a dose- and time-dependent manner."
05/01/2007 - "Rupatadine 10 and 20 mg significantly reduced pruritus severity by 62.05% and 71.87% respectively, from baseline, over a period of 4 weeks compared to reduction with placebo by 46.59% (p < 0.05). "
11/01/2013 - "Data synthesis showed that rupatadine is superior to placebo in relieving the overall allergy symptoms on reflective (SMD: -0.37, 95% CI -0.46 to -0.27; p < 0.00001) and instantaneous (SMD: -0.41, 95% CI -0.71 to -0.11; p = 0.007) assessment, the nasal symptoms considered together (reflective SMD: -0.36, 95% CI -0.48 to -0.25; p < 0.00001; instantaneous SMD: -0.39, 95% CI -0.61 to -0.17; p = 0.0004) or individually and ocular symptoms. "
12/01/2014 - "Rupatadine has a suppressing effect on H1R and B2R gene expression which could add to its efficacy towards allergy and allergy-like conditions."
07/01/2012 - "To determine the effectiveness of rupatadine in inmediate mosquito-bite allergy-confirmed adult patients. "
07/01/2012 - "Rupatadine 10 mg in the treatment of immediate mosquito-bite allergy."
04/01/2010 - "The Scope of Pharmacological and Clinical Effects of Modern Antihistamines, With a Special Focus on Rupatadine: Proceedings from a Satellite Symposium held at the 21st World Allergy Congress, Buenos Aires, December 8, 2009."
|5.||Mastocytosis (Mast-Cell Disease)
07/01/2013 - "In this first comprehensive trial of a sgAH in mastocytosis, rupatadine 20 mg daily for 4 weeks significantly controlled symptoms and improved patients' quality of life."
07/01/2013 - "This randomized, double-blind, placebo-controlled, cross-over trial assessed rupatadine 20 mg daily in the treatment of mastocytosis symptoms in 30 adult patients. "
07/01/2013 - "Rupatadine improves quality of life in mastocytosis: a randomized, double-blind, placebo-controlled trial."
01/01/2015 - "In this reappraisal, we revisit some key properties and pivotal clinical studies of rupatadine and examine new clinical data in more detail including studies that measured health-related quality of life and studies that investigated the efficacy and safety of rupatadine in other indications such as acquired cold urticaria, mosquito bite allergy and mastocytosis."
|1.||Histamine (Histamine Dihydrochloride)
|6.||Histamine Antagonists (Antihistamines)
|9.||Silicon Dioxide (Sand)