rupatadine

01/01/2007 - "Clinical trials show that rupatadine is an effective and generally well tolerated treatment for allergic rhinitis and CIU. "
04/01/2010 - "These positive results could explain the effectiveness of rupatadine in the treatment of persistent allergic rhinitis, as reported in a previous study Further controlled studies need to be conducted to confirm these preliminary findings."
02/01/2016 - "This study reports the efficacy and safety of rupatadine, a modern H1 and PAF antagonist recently authorized in Europe for children with allergic rhinitis and CSU. "
01/01/2015 - "This study, which included a wide cohort of allergic-rhinitis patients, confirmed the clinical benefit of rupatadine when prescribed in clinical practice, even for the most severe symptoms, including nasal congestion."
11/01/2013 - "This systematic review was aimed at identifying in the most important databases, up to January 2013, the double-blind placebo-controlled randomized trials administering rupatadine in allergic rhinitis. "

09/01/2009 - "This responder analysis, using different response levels, shows that the efficacy of rupatadine 10 mg and 20 mg is significantly better as compared to placebo in the treatment of chronic urticaria patients. "
02/01/2016 - "Rupatadine is effective in the treatment of chronic spontaneous urticaria in children aged 2-11 years."
08/19/2023 - "Efficacy and safety of on-demand versus daily rupatadine in chronic spontaneous urticaria: A randomized trial."
12/01/2015 - "Rupatadine in Established Treatment Schemes Improves Chronic Spontaneous Urticaria Symptoms and Patients' Quality of Life: a Prospective, Non-interventional Trial."
09/01/2009 - "This analysis includes the pooled data from two randomized, double-blind, placebo-controlled, multicentre studies in which chronic urticaria patients were treated with rupatadine at different doses. "

01/01/2020 - "Higher efficacy of rupatadine 20 mg and 10 mg versus placebo in patients with perennial allergic rhinitis: a pooled responder analysis."
06/01/2003 - "Rupatadine is clinically effective in relieving symptoms in patients with seasonal and perennial allergic rhinitis. "
01/01/2019 - "Objective: Long-term safety and efficacy of 10- and 20-mg rupatadine in Japanese patients with perennial allergic rhinitis (PAR) were investigated in a 52-week open-label study (JapicCTI-152952, clinicaltrials.jp). "
01/01/2019 - "Long-term safety and efficacy of rupatadine in Japanese patients with perennial allergic rhinitis: a 52-week open-label clinical trial."
01/01/2020 - "The clinical efficacy of rupatadine in terms of responders has not been previously explored in perennial allergic rhinitis (PAR). "

01/01/2010 - "A significant reduction of critical temperature threshold (P < .001) and reduced scores for cold provocation-induced wheal reactions (P = .01), pruritus (P = .005), burning sensation (P = .03), and subjective complaints (P = .03) after rupatadine treatment were also found. "
05/01/2007 - "This randomized, double-blind, placebo-controlled, parallel-group, multicentre, study was designed to assess primarily mean pruritus score (MPS) reduction with rupatadine, 10 and 20 mg, administered once daily for 4 weeks. "
01/01/2020 - "These results suggest the long-term usefulness of rupatadine for pruritus in AD."
06/01/2019 - "The primary efficacy endpoint was change from baseline in the total pruritus score to Week 2 by treatment with rupatadine 10mg once daily. "
06/01/2019 - "To investigate the long-term efficacy and safety of rupatadine in the management of pruritus, and the clinical effect of updosing to 20mg in Japanese adult and adolescent patients. "

09/01/2013 - "However, further clinical trials to evaluate the efficacy of rupatadine in different urticaria subtypes and to test the safety of doses higher than 20 mg are encouraged."
02/01/2016 - "Rupatadine is effective and well tolerated in the relief of urticaria symptoms, improving quality of life over 6 weeks in children with CSU. "
09/01/2013 - "Rupatadine for the treatment of urticaria."
03/01/2021 - "In recent years, clinical efficacy and safety controlled-clinical trials on rupatadine were conducted in children and were based on latest current guidelines using validated tools of allergic rhinitis and urticaria. "
03/01/2021 - "The clinical evidence of second-generation H1-antihistamines in the treatment of allergic rhinitis and urticaria in children over 2 years with a special focus on rupatadine."