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LY 287045

an arginal thrombin inhibitor related to efegatran

Also Known As:

1-tetrahydroisoquinolinyl-prolyl-arginal; D-1-Tiq-Pro-Arg-H; LY-287045; LY287045

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Oligopeptides: 519
    - Dipeptides: 945
      - LY 287045: 1

Experts

1.	Bhattacharya, A: 1 article (05/2001)
2.	Cohen, M L: 1 article (05/2001)
3.	Smith, G F: 1 article (05/2001)

Related Diseases

1.	Neoplasms (Cancer) 05/01/2001 - "To the extent that these findings suggest that LY287045 exhibit dual protease inhibition of endothelial responses, LY287045 may have specific utility in hypotensive inflammatory diseases and in cancer metastases where both trypsin and thrombin have been implicated as causative agents."
2.	Neoplasm Metastasis (Metastasis) 05/01/2001 - "To the extent that these findings suggest that LY287045 exhibit dual protease inhibition of endothelial responses, LY287045 may have specific utility in hypotensive inflammatory diseases and in cancer metastases where both trypsin and thrombin have been implicated as causative agents."

Related Drugs and Biologics

1.	Trypsin
2.	Thrombin
3.	Peptide Hydrolases (Proteases)