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LY 287045
an arginal thrombin inhibitor related to efegatran
Also Known As:
1-tetrahydroisoquinolinyl-prolyl-arginal; D-1-Tiq-Pro-Arg-H; LY-287045; LY287045
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Amino Acids, Peptides, and Proteins: 1
Peptides: 82426
Oligopeptides: 519
Dipeptides: 945
LY 287045: 1
Experts
1.
Bhattacharya, A
: 1 article (05/2001)
2.
Cohen, M L
: 1 article (05/2001)
3.
Smith, G F
: 1 article (05/2001)
Related Diseases
1.
Neoplasms (Cancer)
05/01/2001 - "
To the extent that these findings suggest that LY287045 exhibit dual protease inhibition of endothelial responses, LY287045 may have specific utility in hypotensive inflammatory diseases and in cancer metastases where both trypsin and thrombin have been implicated as causative agents.
"
2.
Neoplasm Metastasis (Metastasis)
05/01/2001 - "
To the extent that these findings suggest that LY287045 exhibit dual protease inhibition of endothelial responses, LY287045 may have specific utility in hypotensive inflammatory diseases and in cancer metastases where both trypsin and thrombin have been implicated as causative agents.
"
Related Drugs and Biologics
1.
Trypsin
2.
Thrombin
3.
Peptide Hydrolases (Proteases)