|1.||Liu, A: 2 articles (11/2000 - 06/2000)|
|2.||Rangarajan, M: 2 articles (11/2000 - 06/2000)|
|3.||Sim, S P: 2 articles (11/2000 - 06/2000)|
|4.||Liu, L F: 2 articles (11/2000 - 06/2000)|
|5.||Kim, J S: 2 articles (11/2000 - 06/2000)|
|6.||Lavoie, E J: 1 article (11/2000)|
|7.||Jin, S: 1 article (06/2000)|
|8.||Pilch, D S: 1 article (06/2000)|
|9.||LaVoie, E J: 1 article (06/2000)|
11/01/2000 - "Significant enhancement in the topoisomerase I poisoning activity and cytotoxicity of 5-phenylterbenzimidazole is observed when the 2"-position is substituted with either a chloro or trifluoromethyl substituent. "
11/01/2000 - "The data indicate that such derivatives do retain similar topo I poisoning activity and possess cytotoxicity equivalent to either 5-bromo- or 5-phenylterbenzimidazole. "
11/01/2000 - "The 6-bromo, 6-methoxy, or 6-phenyl derivatives of both 5-bromo- and 5-phenylterbenzimidazole were synthesized and evaluated for topo I poisoning activity, as well as their cytotoxicity toward human lymphoblastoma cells. "
03/10/1998 - "We have employed a broad range of spectroscopic, calorimetric, DNA cleavage, and DNA winding/unwinding measurements to characterize the DNA binding and topoisomerase I (TOP1) poisoning properties of three terbenzimidazole analogues, 5-phenylterbenzimidazole (5PTB), terbenzimidazole (TB), and 5-(naphthyl[2,3-d]imidazo-2-yl)bibenzimidazole (5NIBB), which differ with respect to the substitutions at their C5 and/or C6 positions. "
|1.||Type I DNA Topoisomerases (Topoisomerase I)
|2.||trioctyl phosphine oxide (TOPO)
|3.||DNA (Deoxyribonucleic Acid)