aryl hydrocarbon receptor-interacting protein

cellular protein that associates with hepatitis B virus X protein; inhibits X transactivation; binds to aryl hydrocarbon receptor
Also Known As:
AIP protein, human; AIP protein, mouse; AKIP protein, human; ARA9 protein, human; AURKAIP1 protein, human; Ah receptor-interacting protein, mouse; Ara9 protein, mouse; XAP2 protein, human; aryl hydrocarbon receptor interacting protein, human; aryl-hydrocarbon receptor-interacting protein, mouse; aurora-A kinase interacting protein, human
Networked: 93 relevant articles (0 outcomes, 7 trials/studies)

Bio-Agent Context: Research Results


1. Korbonits, Márta: 14 articles (11/2014 - 06/2008)
2. Daly, Adrian F: 13 articles (03/2015 - 05/2007)
3. Beckers, Albert: 13 articles (03/2015 - 05/2007)
4. Aaltonen, Lauri A: 9 articles (04/2013 - 05/2006)
5. Trivellin, Giampaolo: 8 articles (02/2016 - 08/2010)
6. Jaffrain-Rea, Marie-Lise: 8 articles (10/2013 - 05/2007)
7. Karhu, Auli: 8 articles (04/2013 - 05/2006)
8. Grossman, Ashley B: 7 articles (09/2015 - 06/2008)
9. Chahal, Harvinder S: 6 articles (04/2014 - 06/2008)
10. Ramamurthy, Visvanathan: 5 articles (05/2014 - 03/2010)

Related Diseases

1. Pituitary Neoplasms (Pituitary Adenoma)
2. Leber Congenital Amaurosis
3. Neoplasms (Cancer)
4. Carney Complex
01/01/2011 - "A genetic defect is evident in some cases; known genetic changes include: multiple endocrine neoplasia type 1 (MEN1); Carney complex; McCune-Albright syndrome; and, more recently identified, aryl hydrocarbon receptor-interacting protein (AIP). "
01/01/2014 - "The genetic alterations responsible for the formation of familial pituitary syndromes include the MEN1 gene, responsible for about 80% of MEN1 cases, the regulatory subunit of the protein kinase A, PRKAR1A, responsible for about 70% of Carney complex cases, and AIP, the gene coding the aryl hydrocarbon receptor interacting protein, responsible for about 20% of FIPA cases. "
01/01/2011 - "To date, the number of molecular genetic factors unequivocally linked to pituitary tumours can be counted on the fingers of one hand: (1) GNAS1 activation in acromegaly; (2) the MENIN and p27Kip1 (CDKN1B) mutations associated with multiple endocrine neoplasia type 1; (3) mutations of PRKA1RA with loss of 17q22-24 in Carney complex, and (4) aryl hydrocarbon receptor interacting protein gene mutations in 15% of familial isolated pituitary adenomas and 50% of familial isolated acromegaly. "
03/01/2008 - "GNAS1 activation and the mutations associated with multiple endocrine neoplasia type 1 and Carney complex, aryl hydrocarbon receptor interacting protein gene mutations, and a narrowing region of chromosome 11q13 in familial isolated acromegaly together account for such a small proportion of pituitary adenomas that the pituitary adenoma pathogenic epiphany is surely yet to come."
02/01/2016 - "Prior studies have identified gigantism as a feature of a number of monogenic disorders, including mutations in the aryl hydrocarbon receptor interacting protein gene, multiple endocrine neoplasia types 1 and 4, McCune Albright syndrome, Carney complex, and the paraganglioma, pheochromocytoma, and pituitary adenoma association because of succinate dehydrogenase defects. "
5. Multiple Endocrine Neoplasia (Multiple Endocrine Adenomatosis)

Related Drugs and Biologics

1. Proteins (Proteins, Gene)
2. MicroRNAs (MicroRNA)
3. Succinate Dehydrogenase (Fumarate Reductase)
4. DNA (Deoxyribonucleic Acid)
5. Carbon Monoxide
6. Cyclin-Dependent Kinase Inhibitor p27
7. Growth Hormone (Somatotropin)
8. Prolactin
9. Hormones
10. beta Catenin