5,7,4'-trimethylapigenin

a flavonoid from the East Asian medicinal plant Orthosiphon spicatus; prevents oxidative inactivation of 15-lipoxygenase; structure given in first source

Also Known As:

4',5,7-trimethoxyflavone; 4',5,7-trimethyl-apigenin

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrans: 130
    - Benzopyrans: 195
      - Chromones: 159
        Flavonoids: 9773
        Flavones: 446
        Apigenin: 1098
        5,7,4'-trimethylapigenin: 1
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzopyrans: 195
      - Chromones: 159
        Flavonoids: 9773
        Flavones: 446
        Apigenin: 1098
        5,7,4'-trimethylapigenin: 1

Experts

1.	Feng, Chunlai: 1 article (01/2022)
2.	Li, Qinglin: 1 article (01/2022)
3.	Qin, Jiang-Jiang: 1 article (01/2022)
4.	Yu, Xuefei: 1 article (01/2022)
5.	Zhang, Lizhuo: 1 article (01/2022)
6.	Zhu, Xuhang: 1 article (01/2022)

Related Diseases

Thyroid Neoplasms (Thyroid Cancer)

01/01/2022 - "Further characterization revealed a significant inhibitory effect of 4',5,7-trimethoxyflavone on PDGFRA-MAPK pathway activation, and that it could upregulate expression of sodium iodide symporter (NIS) as well as improve radioiodine uptake capacity of radioiodine-refractory thyroid cancer (RAIR-TC), suggesting it a potential drug lead for the development of new RAIR-TC therapy."

Related Drugs and Biologics

1.	sodium-iodide symporter (sodium iodide symporter)

Related Therapies and Procedures

1.	Therapeutics