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SNC 121

RN given for (2S-(1(S+),2alpha,5beta))-isomer; structure in first source

Also Known As:

SNC-121; SNC121

Networked: 4 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Guzman, Wendy: 2 articles (01/2021 - 01/2020)
2.	Husain, Shahid: 2 articles (01/2021 - 01/2020)
3.	Mehrotra, Shikhar: 2 articles (01/2021 - 01/2020)
4.	Singh, Sudha: 2 articles (01/2021 - 01/2020)
5.	Zaidi, Syed A H: 2 articles (01/2021 - 01/2020)
6.	Patel, Hemal H: 2 articles (11/2010 - 09/2007)
7.	Roth, David M: 2 articles (11/2010 - 09/2007)
8.	Tsutsumi, Yasuo M: 2 articles (11/2010 - 09/2007)
9.	Gangaraju, Vamsi: 1 article (01/2020)
10.	Thakore, Nakul: 1 article (01/2020)

Related Diseases

1.	Glaucoma 01/01/2021 - "The main objective of this study was to determine the inhibition of pro-inflammatory cytokines and their associated signaling molecules by δ-opioid receptor activation by a selective ligand, SNC-121 in chronic rat glaucoma model. "
2.	Ocular Hypertension (Glaucoma, Suspect) 01/01/2021 - "Data illustrated that SNC-121 administration completely abrogated ocular hypertension-induced increase in STAT3Y705 phosphorylation. " 01/01/2020 - "Our data also demonstrate that SNC-121 treatment decrease glial fibrillary acidic protein immunostaining in the optic nerves of animals with ocular hypertension."
3.	Myocardial Ischemia (Ischemic Heart Diseases) 11/01/2010 - "Cav-3 overexpressing mice, Cav-3 knockout mice, and controls were exposed to myocardial ischemia/reperfusion (I/R) in the presence of SNC-121 (SNC), a δ-selective opioid agonist, or naloxone, a nonselective opioid antagonist. "
4.	Ischemia 09/22/2007 - "Mice were subjected to 30 min coronary artery occlusion followed by 2 h of reperfusion with or without ischemic or pharmacologic PostC (three cycles of 20 s reperfusion/ischemia; 1.4% isoflurane; 10 mg/kg SNC-121). "

Related Drugs and Biologics

1.	Cytokines
2.	Opioid Receptors (Opioid Receptor)
3.	Ligands
4.	Narcotic Antagonists (Opioid Antagonists)
5.	Naloxone (Narcan)
6.	Isoflurane
7.	Glial Fibrillary Acidic Protein
8.	Opioid Analgesics (Opioids)