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adenosine-5'-carboxylic acid
Also Known As:
Ado-5'-COOH; adenosine 5'-carboxylic acid
Networked:
5
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
Fused-Ring Heterocyclic Compounds
2-Ring Heterocyclic Compounds
Purines: 651
Purine Nucleosides: 360
Adenosine: 12431
adenosine-5'-carboxylic acid: 5
Nucleic Acids, Nucleotides, and Nucleosides: 1
Nucleosides: 6847
Purine Nucleosides: 360
Adenosine: 12431
adenosine-5'-carboxylic acid: 5
Ribonucleosides: 49
Adenosine: 12431
adenosine-5'-carboxylic acid: 5
Related Diseases
1.
Glioma (Gliomas)
12/13/1996 - "
Here we describe the synthesis of a new class of compounds, peptidyl derivatives of adenosine 5'-carboxylic acid, among which some have inhibitory effects in certain P2 purinoceptor-carrying biological systems, e.g., glioma and smooth muscle cell lines and isolated smooth muscle tissue preparations from guinea pig vas deferens and urinary bladder.
"
10/01/1994 - "
The tri- and tetra-aspartic acid derivatives of adenosine-5'-carboxylic acid (AdoCAsp3 and AdoCAsp4) were found to act as weak agonists at P2-purinergic receptors, (activated by ATP and UTP respectively) present on C6 glioma cells.
"
2.
Acidosis
01/01/1976 - "
Haemodynamic effects of adenosine-5'-carboxylic acid-amide in the anaesthetized dog during normal respiration and hypercapnic acidosis.
"
01/01/1975 - "
Proceedings: Comparison of the haemodynamic effects of adenosine-5'-carboxylic acid-amide and adenosine under normal ventilation and under hypercapnic acidosis.
"
3.
Tachycardia (Tachyarrhythmias)
08/08/1975 - "
Short-chain aliphatic esters and amides of adenosine-5'-carboxylic acid caused marked increases in coronary sinus oxygen tension (PO2) in the dog; the amides were generally more potent, causing additionally marked hypotension and tachycardia.
"
4.
Hypotension (Low Blood Pressure)
08/08/1975 - "
Short-chain aliphatic esters and amides of adenosine-5'-carboxylic acid caused marked increases in coronary sinus oxygen tension (PO2) in the dog; the amides were generally more potent, causing additionally marked hypotension and tachycardia.
"
Related Drugs and Biologics
1.
Amides
2.
Purinergic P2 Receptors (ADP Receptor)
3.
Uridine Triphosphate (UTP)
4.
Oxygen (Dioxygen)
5.
Esters
6.
Aspartic Acid (Aspartate)
7.
Adenosine Triphosphate (ATP)
8.
Adenosine (Adenocard)