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B 4157

structure given in first source

Also Known As:

B-4157; B4157

Networked: 1 relevant articles (1 outcomes, 0 trials/studies)

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Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 3-Ring Heterocyclic Compounds
    - Phenazines: 42
      - Clofazimine: 767
        B 4157: 1

Related Diseases

1.	Body Weight (Weight, Body) 03/01/1996 - "At a dose of 20 mg/kg of body weight, the activity of CFM was slightly superior to that of B4157; however, both compounds prevented mortality and caused a significant reduction in the numbers of CFU in the lungs and spleens. "
2.	Multidrug-Resistant Tuberculosis (Drug-Resistant Tuberculosis) 03/01/1996 - "Complete susceptibility of multidrug-resistant strains to CFM and B4157 and the therapeutic efficacies of these compounds against mouse tuberculosis make these drugs attractive agents for the treatment of drug-resistant tuberculosis."
3.	Tuberculosis (Tuberculoses) 03/01/1996 - "Complete susceptibility of multidrug-resistant strains to CFM and B4157 and the therapeutic efficacies of these compounds against mouse tuberculosis make these drugs attractive agents for the treatment of drug-resistant tuberculosis." 03/01/1996 - "In our efforts to develop new drugs for the treatment of tuberculosis, especially that caused by multidrug-resistant strains, we investigated clofazimine (CFM) and two of its analogs, B4154 and B4157, for their antituberculosis activities. "

Related Drugs and Biologics

1.	Clofazimine (Lamprene)
2.	B 4154