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hirunorm

a 26-amino acid peptide; differs from hirunorm IV in the second amino acid - Val(2) instead of Arg(2); amino acid sequence in first source

Also Known As:

hirunorm V

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - hirunorm: 1

Related Diseases

1.	Venous Thrombosis (Deep-Vein Thrombosis) 09/01/1996 - "Intravenous and subcutaneous hirunorm inhibited venous thrombosis at doses (< or = 0.3 mg/kg) two-three times higher than those of r-hirudin. "
2.	Thrombosis (Thrombus) 09/01/1996 - "In conclusion, hirunorm is a potent peptide thrombin inhibitor endowed with antithrombotic activity in models of venous and arterial thrombosis." 09/01/1996 - "Arterial thrombosis was obtained in the anaesthetized rat by chemical (FeCl2) stimulation of a common carotid and i.v. infused hirunorm (1-3 mg/kg/30 min) inhibited it dose-dependently; r-hirudin was partly active only at 3 mg/kg, but hirulog-1 was inactive at either dose. "

Related Drugs and Biologics

1.	Thrombin
2.	Peptides (Polypeptides)
3.	Hirudins
4.	bivalirudin (Angiomax)