TEL-AML1 fusion protein

product of fusion of TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoplastic leukemia

Also Known As:

ETV6-AML1 protein; ETV6-CBFA2 fusion protein; ETV6-RUNX1 fusion protein, human; MDS-1-EVI1 fusion protein; TEL-AML1 protein

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

1.	Neoplasms (Cancer) 07/15/1998 - "In this study, we have examined whether the chimeric ETV6-AML1 protein could serve as a tumor specific antigen for CTL in HLA-A2.1 individuals. "
2.	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 12/03/2015 - "The TEL-AML1 fusion protein of acute lymphoblastic leukemia modulates IRF3 activity during early B-cell differentiation." 01/28/1999 - "A cytogenetically cryptic (12;21) translocation is the most common molecular abnormality identified in childhood acute lymphoblastic leukemia (ALL), and it generates a chimeric TEL-AML1 protein. " 07/15/1998 - "Cytotoxic T cell response against the chimeric ETV6-AML1 protein in childhood acute lymphoblastic leukemia."

1.	Antigens