HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

poly(lactic-glycolic acid)-poly(ethyleneglycol) copolymer

structure given in first source
Also Known As:
PLGA-PEG copolymer; PLGA-b-PEG; poly(D,L-lactic-co-glycolic acid)-block-poly(ethylene glycol)
Networked: 17 relevant articles (1 outcomes, 3 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Farokhzad, Omid C: 6 articles (01/2015 - 04/2006)
2. Langer, Robert: 4 articles (01/2010 - 04/2006)
3. Paulmurugan, Ramasamy: 3 articles (12/2020 - 03/2015)
4. Dhar, Shanta: 3 articles (10/2012 - 11/2008)
5. Devulapally, Rammohan: 2 articles (06/2015 - 03/2015)
6. Sekar, Thillai V: 2 articles (06/2015 - 03/2015)
7. Lippard, Stephen J: 2 articles (02/2011 - 11/2008)
8. Bidkar, Anil P: 1 article (11/2021)
9. Blaha, Charles: 1 article (11/2021)
10. Desai, Tejal A: 1 article (11/2021)

Related Diseases

1. Neoplasms (Cancer)
12/01/2020 - "In this study, a clinically relevant, minimally invasive ultrasound guided therapeutic approach is investigated for targeted delivery of anticancer microRNA loaded PLGA-b-PEG nanoparticles to spontaneous hepatocellular neoplasia in a canine model. "
03/24/2015 - "We synthesized the antisense-miR-21 and antisense-miR-10b loaded PLGA-b-PEG polymer NPs and evaluated their cellular uptake, serum stability, release profile, and the subsequent synchronous blocking of endogenous miR-21 and miR-10b function in TNBC cells in culture, and tumor xenografts in living animals using molecular imaging. "
10/02/2012 - "Considering efficacy, the targeted PLGA-b-PEG-TPP NP provides a remarkable improvement in the drug therapeutic index for cancer, Alzheimer's disease, and obesity compared with the nontargeted construct or the therapeutics in their free form. "
11/11/2008 - "A comparison between the cytotoxic activities of Pt(IV)-encapsulated PLGA-b-PEG NPs with the PSMA aptamer on the surface (Pt-NP-Apt), cisplatin, and the nontargeted Pt(IV)-encapsulated NPs (Pt-NP) against human prostate PSMA-overexpressing LNCaP and PSMA(-) PC3 cancer cells revealed significant differences. "
07/10/2015 - "Using the reaction of non-small cell lung cancer (SK-MES-1 and A549 cell lines) as representative of other cancer types', the present study examines the effects of EpCAM-fluoropyrimidine RNA aptamer-decorated, DOX-loaded, PLGA-b-PEG nanopolymersomes that bond specifically to the extracellular domain of epithelial-cell adhesion molecules. "
2. Alzheimer Disease (Alzheimer's Disease)
3. Obesity
4. Hepatocellular Carcinoma (Hepatoma)
5. Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)

Related Drugs and Biologics

1. Ethylene Glycol (Monoethylene Glycol)
2. Polylactic Acid-Polyglycolic Acid Copolymer
3. Nucleotide Aptamers
4. MicroRNAs (MicroRNA)
5. 2-Methoxyestradiol
6. Epithelial Cell Adhesion Molecule
7. fosbretabulin (combretastatin A4)
8. poly(lactic-glycolic acid)-poly(ethyleneglycol) copolymer
9. Antigens
10. antineoplaston A10 (A 10)

Related Therapies and Procedures

1. Therapeutics
2. Drug Therapy (Chemotherapy)