|1.||Choi, Wahn Soo: 5 articles (01/2010 - 03/2007)|
|2.||Han, Jeung-Whan: 5 articles (07/2009 - 01/2002)|
|3.||Kim, Hyung Sik: 4 articles (12/2012 - 04/2008)|
|4.||Cheng, Li-Hao: 3 articles (01/2014 - 01/2013)|
|5.||Huang, Chih-Yang: 3 articles (01/2014 - 01/2013)|
|6.||Chen, Ming-Cheng: 3 articles (01/2014 - 01/2013)|
|7.||Hsu, Hsi-Hsien: 3 articles (01/2014 - 01/2013)|
|8.||Lin, Yueh-Min: 3 articles (01/2014 - 01/2013)|
|9.||Tsai, Fuu-Jen: 3 articles (01/2014 - 01/2013)|
|10.||Ahn, Mee Young: 3 articles (12/2012 - 05/2009)|
11/01/2011 - "The aim of this study was to evaluate the anti-tumor efficacy of apicidin through apoptosis and autophagy in OSCC cells. "
11/22/2013 - "Since their discovery in 1996 a multitude of studies concerning the activity against protozoa and certain cancer cell lines of natural and synthetic apicidin analogues have been published. "
05/15/2009 - "This study examined the anti-tumor effects of apicidin in Ishikawa cancer cells. "
04/01/2015 - "These results suggested that apicidin is an attractive chemotherapeutic agent against salivary MEC and may be a good candidate for targeting IGF-1R for cancer therapies. "
12/31/2013 - "Apicidin-resistant (Apicidin- R) HA22T cells are known to activate the Wnt/β-catenin signaling pathway and MMP-2 expression via the IGF-IR/PI3K/Akt signaling pathway to enhance metastatic effects of cancer cells. "
|2.||Ovarian Neoplasms (Ovarian Cancer)
02/01/2007 - "The findings raise the possibility that apicidin may prove particularly effective in the treatment of endometrial and ovarian cancers."
12/28/2012 - "This study examined the molecular mechanisms of apicidin in the modulation of human ovarian cancer SKOV-3 cells invasion and migration. "
02/01/2007 - "MTT assays showed that all endometrial and ovarian cancer cell lines were sensitive to the growth inhibitory effect of apicidin, although normal endometrial epithelial cells were viable after the treatment with the same doses of apicidin that induced the growth inhibition of endometrial and ovarian cancer cells. "
02/01/2007 - "Endometrial and ovarian cancer cells were treated with various concentrations of apicidin, and the effects on cell growth, cell cycle, apoptosis and related measurements were investigated. "
02/01/2007 - "Our purpose was to investigate the antiproliferative effects of a novel HDACI, apicidin, on the Ishikawa endometrial cancer cell line, the SK-OV-3 ovarian cancer cell line and normal human endometrial epithelial cells. "
|3.||Autoimmune Diseases (Autoimmune Disease)
|4.||Endometrial Neoplasms (Endometrial Cancer)
01/01/2010 - "The expression patterns of a specific HDAC class by apicidin were measured in Ishikawa endometrial cancer both in vitro and in vivo. "
05/15/2009 - "Mechanism of apicidin-induced cell cycle arrest and apoptosis in Ishikawa human endometrial cancer cells."
01/01/2010 - "This study examined the anti-tumor effect of apicidin on human endometrial cancer Ishikawa cells in an animal model by inhibiting specific HDAC expression. "
01/01/2010 - "We suggest that apicidin is an effective anti-tumor agent on human endometrial cancer cells, and acts by regulating cell proliferation and apoptosis through the down-regulation of HDAC3 and HDAC4."
05/15/2009 - "These results suggest that apicidin has anti-tumor properties on endometrial cancer cells by inducing selectively the genes related to cell cycle arrest and apoptosis."
03/09/2001 - "In this study, we show apicidin induces transcriptional activation of p21(WAF1/CIP1) (p21) in human prostate carcinoma cells. "
07/02/2015 - "In vitro cytotoxicity evaluation of HDAC inhibitor Apicidin in pancreatic carcinoma cells subsequent time and dose dependent treatment."
07/15/2009 - "Interestingly, embryonic carcinoma cells (NCCIT, NTERA2, and P19) exhibit a higher sensitivity to apicidin in down-regulation of Nanog compared with embryonic stem cells. "
|1.||Histone Deacetylase Inhibitors
|2.||Histone Deacetylases (Histone Deacetylase)
|3.||Proteins (Proteins, Gene)
|8.||Proteasome Endopeptidase Complex (Proteasome)
|1.||Heterologous Transplantation (Xenotransplantation)