|1.||Kanazawa, Kazuki: 3 articles (10/2012 - 12/2005)|
|2.||Maruta, H: 3 articles (12/2011 - 02/2009)|
|3.||Hori, Hitoshi: 3 articles (03/2009 - 07/2007)|
|4.||Uto, Yoshihiro: 3 articles (03/2009 - 07/2007)|
|5.||Arai, S: 3 articles (03/2001 - 09/2000)|
|6.||Micallef, M J: 3 articles (03/2001 - 09/2000)|
|7.||Hanaya, T: 3 articles (03/2001 - 09/2000)|
|8.||Kimoto, T: 3 articles (03/2001 - 09/2000)|
|9.||Kurimoto, M: 3 articles (03/2001 - 09/2000)|
|10.||Hino, K: 3 articles (03/2001 - 09/2000)|
|1.||Colonic Neoplasms (Colon Cancer)
12/01/2005 - "Artepillin C appears to prevent colon cancer through the induction of cell-cycle arrest by stimulating the expression of Cip1/p21 and to be a useful chemopreventing factor in colon carcinogenesis."
12/01/2005 - "Artepillin C was then added to human colon cancer WiDr cells. "
08/18/2006 - "In this study, artepillin C was tested for colon cancer-preventing activity using azoxymethane-challenged ddY mice. "
12/01/2005 - "Artepillin C in Brazilian propolis induces G(0)/G(1) arrest via stimulation of Cip1/p21 expression in human colon cancer cells."
10/01/2012 - "A pilot, randomized, placebo-controlled, double-blind phase 0/biomarker study on effect of artepillin C-rich extract of Brazilian propolis in frequent colorectal adenoma polyp patients."
03/01/2001 - "In contrast, after oral administration of propolis or artepillin C, adenomas did not progress to carcinomas. "
03/01/2001 - "Instead of developing into large cell cancers, as induced by Fe-NTA in control mice, adenomas showed remarkable proliferation of macrophages and local anti-oxidant activity after treatment with either propolis or artepillin C. "
07/18/2007 - "Artepillin C may prove useful in the development of agents and foods with therapeutic or preventive activity against tumor angiogenesis."
01/01/1998 - "When artepillin C was applied to human and murine malignant tumor cells in vitro and in vivo, artepillin C exhibited a cytotoxic effect and the growth of tumor cells was clearly inhibited. "
07/18/2007 - "Suppression of tumor-induced angiogenesis by Brazilian propolis: major component artepillin C inhibits in vitro tube formation and endothelial cell proliferation."
01/01/2001 - "Artepillin C (3,5-diprenyl-4-hydroxycinnamic acid) is an active ingredient of Brazilian propolis that possesses anti-tumor activity. "
01/01/1998 - "The artepillin C was found to cause significant damage to solid tumor and leukemic cells by the MTT assay, DNA synthesis assay, and morphological observation in vitro. "
|1.||Propolis (Bee Bread)
|3.||caffeic acid phenethyl ester
|4.||Histone Deacetylase Inhibitors
|6.||Glutamic Acid (Glutamate)
|7.||NF-kappa B (NF-kB)
|10.||Glutathione (Reduced Glutathione)
|1.||Heterologous Transplantation (Xenotransplantation)