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Streptomyces FK506 macrolide 9-hydroxylase

catalyzes hydroxylation at position C-9 of the FK506 and FK520 macrolactone ring; isolated from Streptomyces; FK506 and FK520 are 23-membered macrocyclic polyketides with potent immunosuppressive and antifungal activities
Also Known As:
FK506 macrolide 9-hydroxylase, Streptomyces; FK520 macrolide 9-hydroxylase, Streptomyces; FkbD protein, Streptomyces; cytochrome P-450 9-deoxo-FK506 hydroxylase, Streptomyces
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Bio-Agent Context: Research Results