|1.||Massi, Maurizio: 4 articles (11/2009 - 05/2002)|
|2.||Anthes, John: 4 articles (09/2009 - 12/2008)|
|3.||Fernandez, Xiomara: 4 articles (09/2009 - 12/2008)|
|4.||Tulshian, Deen: 4 articles (09/2009 - 12/2008)|
|5.||McLeod, Robbie L: 4 articles (09/2009 - 12/2008)|
|6.||Greenlee, William J: 4 articles (09/2009 - 12/2008)|
|7.||Takeshima, Hiroshi: 4 articles (01/2008 - 06/2003)|
|8.||Zaveri, Nurulain T: 3 articles (12/2015 - 12/2009)|
|9.||Borsodi, Anna: 3 articles (07/2013 - 10/2007)|
|10.||Simonato, Michele: 3 articles (11/2012 - 11/2002)|
12/01/2015 - "Small-molecule nociceptin receptor agonist ameliorates mast cell activation and pain in sickle mice."
02/01/2006 - "In the present study, we examined the relationship of pain responses between PGs and N/OFQ using the N/OFQ receptor (NOP) antagonist, N-(4-amino-2-methylquinolin-6-yl)-2-(4-ethylphenoxy-methyl)benzamide monohydrochloride (JTC-801), and in mice lacking the N/OFQ prepropeptide (ppN/OFQ(-/-)) and the NOP receptor (NOP(-/-)). "
01/01/2012 - "This is particularly intriguing because the NOP receptor/nociceptin system has been primarily linked to behavior and pain regulation, but a role in CNS development or myelination has not been described before. "
01/08/2008 - "Nociceptin-receptor deficiency prevents postherpetic pain without effects on acute herpetic pain in mice."
09/01/2006 - "Thus, NC and the ORL1 receptor may be involved in the modulation of neuropathic and inflammatory pain at the level of the primary afferent neuron."
05/15/2012 - "Inhibition of the N/OFQ receptor (NOP) by SB612111 significantly ameliorated the clinical disease course in these animals, as indicated by reduced fecal bleeding, improved recovery from diarrhea and weight loss, and a reduction in histopathological alterations. "
11/01/2014 - "Activation of the endogenous nociceptin system by selective nociceptin receptor agonist SCH 221510 produces antitransit and antinociceptive effect: a novel strategy for treatment of diarrhea-predominant IBS."
|3.||Weight Loss (Weight Reduction)
04/06/1999 - "In the present study, we identified the expression of the ORL1 receptor in murine N1E-115 neuroblastoma cells and used this neuronal system to investigate the pharmacological activity of Phe(phi)noc. "
10/08/2001 - "We investigated NC-induced internalization and recycling of the ORL1 receptor in SK-N-BE human neuroblastoma cells. "
09/29/1999 - "Likewise, chronic activation of endogenous ORL1 receptors in the neuroblastoma SK-N-SH cells led to Gi/Go-mediated AC supersensitization."
09/30/2002 - "The present study sought to determine the molecular mechanism(s) by which OFQ/N modulates the chronic actions of morphine by utilizing human neuroblastoma cell lines [BE(2)-C and SH-SY5Y] that endogenously express TH, and mu and ORL1 receptors. "
02/01/2013 - "Here we show that RGS19 is abundantly expressed in human neuroblastoma SH-SY5Y cells that also express µ- and δ- opioid receptors (MORs and DORs, respectively) and nociceptin receptors (NOPRs). "
|1.||Neurokinin-1 Receptors (Neurokinin 1 Receptor)
|3.||Opioid Receptors (Opioid Receptor)
|4.||Morphine (MS Contin)
|6.||GTP-Binding Proteins (G-Protein)