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chlovalicin
isolated from Sporothrix; structure in first source
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Ketones: 2618
Cyclohexanones: 5
chlovalicin: 1
Hydrocarbons: 1713
Cyclic Hydrocarbons: 97
Alicyclic Hydrocarbons: 1
Cycloparaffins: 6
Cyclohexanes: 3
Cyclohexanones: 5
chlovalicin: 1
Ethers: 242
Cyclic Ethers: 12
Epoxy Compounds: 689
chlovalicin: 1
Related Diseases
1.
Experimental Melanoma
07/01/1996 - "
Chlovalicin, a ovalicin derivative with a chlorinated methylene moiety at the C-1 position of the cyclohexane ring, dose-dependently inhibited the growth of IL-6 dependent MH60 cells (IC50, 7.5 microM) in the presence of 0.2 U/ml IL-6 and, to a lesser extent, the growth of B16 melanoma cells (IC50, 38 microM).
"
Related Drugs and Biologics
1.
Interleukin-6 (Interleukin 6)
2.
Cyclohexane
3.
ovalicin