sildenafil (Viagra)

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1875 relevant articles (379 outcomes, 386 trials/studies) found for this Drug

Description: A 7,8-pyrazolo-pyrimidine, differing from PURINES which are 7,9-pyrazolo-pyrimidines; Viagra (tradename) is sildenafil citrate, used in oral therapy for male erectile dysfunction

Also Known As:

Viagra; sildenafil citrate; 1-((3-(6,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-d)pyrimidin-5-yl)-4-ethoxyphenyl)sulfonyl)-4-methylpiperazine citrate; Abbott brand of sildenafil citrate; Pfizer brand 1 of sildenafil citrate; Pfizer brand 2 of sildenafil citrate; Revatio; UK 92480-10; UK-92,480-10; acetildenafil; desmethyl sildenafil; desmethylsildenafil; homosildenafil; hydroxyhomosildenafil

Relationship Network

Drug Context: Research Results

Heterocyclic Compounds: 25

1-Ring Heterocyclic Compounds

Piperazines: 17

sildenafil: 1875

2-Ring Heterocyclic Compounds

Purines: 354

sildenafil: 1875

Organic Chemicals: 42

Sulfur Compounds: 87

Sulfones: 121

sildenafil: 1875

Experts

1.	Grimminger, Friedrich: 12 articles (01/2008 - 04/2002)
2.	Seeger, Werner: 9 articles (01/2008 - 04/2002)
3.	Tseng, Li-Jung: 8 articles (04/2008 - 11/2005)
4.	Althof, Stanley E: 8 articles (04/2008 - 04/2004)
5.	Ghofrani, Hossein A: 8 articles (01/2008 - 04/2003)
6.	Cappelleri, Joseph C: 7 articles (04/2008 - 11/2005)
7.	Weissmann, Norbert: 7 articles (01/2008 - 04/2002)
8.	Olschewski, Horst: 7 articles (01/2008 - 04/2002)
9.	Montorsi, Francesco: 7 articles (07/2007 - 01/2003)
10.	Dias-Junior, Carlos A: 6 articles (10/2008 - 01/2005)

Related Diseases

1.	Erectile Dysfunction 03/01/2006 - "A combined approach of sildenafil and sex therapy proved highly effective in treatment of honeymoon impotence of psychogenic origin; however, controlled studies are needed. " 08/01/2005 - "Sildenafil, a highly selective inhibitor of PDE 5, is effective in the treatment of erectile dysfunction. " 07/01/2005 - "OBJECTIVES: Most of the available data on efficacy for sildenafil are based on a questionnaire and erectile dysfunction (ED) is classified with minor or severe organic factors. " 04/01/2004 - "Sildenafil, a highly selective inhibitor of phosphodiesterase type 5, is effective in the treatment of erectile dysfunction. " 12/20/2000 - "CONCLUSIONS: In most patients with good sleep efficiency and who have erectile dysfunction, sildenafil, rather than a placebo, taken at bedtime produces a significantly improved nocturnal erectile activity. " Order ALL the reference details at left...
2.	Pulmonary Hypertension (Ayerza Syndrome) 01/01/2006 - "CONCLUSIONS: Sildenafil has beneficial effects on cerebral vascular reactivity indicative of an improvement in neurovascular coupling in patients with pulmonary hypertension. " 07/01/2002 - "Sildenafil, a pulmonary vasodilator, is likely to be beneficial in primary pulmonary hypertension. " 08/01/2009 - "CONCLUSION: Long-term use of sildenafil in patients with secondary forms of pulmonary hypertension is associated with a sustained improvement in cardio-pulmonary haemodynamics. " 10/01/2009 - "Oral sildenafil is effective for pulmonary hypertension and right ventricular support. " 01/01/2008 - "BACKGROUND: Sildenafil has been shown to be effective in the treatment of pulmonary hypertension, and has favourable effects on endothelial function. " Order ALL the reference details at left...
3.	Hypertension (High Blood Pressure) 06/01/2005 - "Clinical studies have demonstrated that sildenafil successfully treats ED of varied organic, psychogenic or mixed aetiology, and is effective in men with ED and comorbidities such as hypertension, hyperlipidaemia, diabetes or depression. " 02/01/2008 - "After increasing the sildenafil dose to ensure therapeutic drug levels over 24 hours, the pulmonary arterial hypertension and physical performance of the patient improved significantly. " 04/20/2005 - "Sildenafil use in children appears to be safe and may be beneficial in the management of pulmonary arterial hypertension." 10/01/2009 - "Sildenafil has been suggested to be a cost-effective treatment for pulmonary arterial hypertension (PAH). " 03/01/2009 - "To date, PDE5 inhibition has been shown to be effective for the treatment of idiopathic pulmonary artery hypertension, and sildenafil is approved for this indication. " Order ALL the reference details at left...
4.	Prostatic Neoplasms (Prostate Cancer) 01/01/2005 - "Subsequently, sildenafil has been reported to be effective in men with ED associated with diabetes and prostate cancer, and in psychogenic ED. " 12/01/2001 - "CONCLUSION: Sildenafil is well tolerated and effective in improving erectile function of patients with ED after 3D-CRT for prostate cancer." 04/01/2001 - "CONCLUSIONS: In men receiving 3DCRT for prostate cancer, these data indicate that sildenafil citrate is effective for restoring SF and associated satisfaction back to baseline before treatment." 07/01/2005 - "The efficacy of sildenafil citrate following radiation therapy for prostate cancer: temporal considerations." 04/01/2009 - "AIM: To define the predictors of sildenafil response in men treated with RT for prostate cancer. " Order ALL the reference details at left...
5.	Heart Failure 12/01/2004 - "Oral sildenafil is safe and effective for the evaluation of PH reactivity in heart failure." 09/01/2004 - "Sildenafil was safe and improved erectile function and quality of life in men with moderately severe congestive heart failure." 08/01/2009 - "Following acute administration and with chronic therapy for up to 6 months sildenafil improved hemodynamic parameters and exercise capacity in patients with PH and chronic left heart failure. " 02/01/2008 - "Endothelium-mediated modulation of ergoreflex and improvement in exercise ventilation by acute sildenafil in heart failure patients." 10/02/2007 - "Sildenafil treatment also was associated with improvement in 6-minute walk distance (29 m versus placebo; P=0.047) and Minnesota Living With Heart Failure score (-14 versus placebo; P=0.01). " Order ALL the reference details at left...

Related Drugs and Biologics

1.	sildenafil (Viagra)
2.	Type 5 Cyclic Nucleotide Phosphodiesterases
3.	tadalafil (Cialis)
4.	vardenafil (Levitra)
5.	bosentan (Tracleer)
6.	Epoprostenol (Prostacyclin)
7.	Alprostadil (Muse)
8.	Testosterone (Sustanon)
9.	5'-Guanylic Acid (GMP)
10.	beraprost

Related Therapies and Procedures

1.	Prostatectomy (Retropubic Prostatectomy)
2.	Brachytherapy
3.	Renal Dialysis (Hemodialysis)
4.	Transplantation (Transplant Recipients)
5.	Kidney Transplantation

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