|1.||Yates, Clayton: 2 articles (01/2015 - 01/2014)|
|2.||Dean-Colomb, Windy: 2 articles (01/2015 - 01/2014)|
|3.||Arora, Ritu: 2 articles (01/2015 - 01/2014)|
|4.||Tan, Ming: 2 articles (01/2015 - 01/2014)|
|5.||Schmitt, David: 1 article (01/2015)|
|6.||Karanam, Balasubramanyam: 1 article (01/2015)|
|7.||Reed, Eddie: 1 article (01/2014)|
|8.||Gary, Bernard D: 1 article (01/2014)|
|9.||Owen, Laurie B: 1 article (01/2014)|
|10.||McClellan, Steven: 1 article (01/2014)|
|1.||Breast Neoplasms (Breast Cancer)
01/01/2014 - "Here we report for the first time the anti-tumor activity of panepoxydone (PP), a NF-κB inhibitor isolated from an edible mushroom, in several breast cancer cell lines. "
01/01/2014 - "Panepoxydone targets NF-kB and FOXM1 to inhibit proliferation, induce apoptosis and reverse epithelial to mesenchymal transition in breast cancer."
01/20/2015 - "Panepoxydone (PP), a natural NF-kB inhibitor, significantly reduces the oxygen consumption and lactate production of MCF-7 and triple negative (MDA-MB-231, MDA-MB-468 and MDA-MB-453) breast cancer cells. "
05/01/2007 - "DNA microarray analysis of 110 human genes known to be strongly regulated during inflammation, combined with reverse transcription quantitative real-time polymerase chain reaction (RT-qPCR) revealed that low micromolar concentrations (12-24 microM) of panepoxydone strongly inhibited the expression of thirty-three NF-kappaB dependent pro-inflammatory genes such as the chemokines CCL3, CCL4, CCL8; CXCL8, CXCL10, CXCL20, the cytokines IL-1, IL-6, TNF-alpha, pro-inflammatory enzymes like COX-2, and components of the REL/NF-kappaB/IkappaB family without significant effects on the expression of house-keeping genes. "
|1.||NF-kappa B (NF-kB)
|5.||Interleukin-6 (Interleukin 6)
|6.||Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
|7.||Interleukin-1 (Interleukin 1)
|9.||DNA (Deoxyribonucleic Acid)