Nocardia delipidated cell mitogen

09/01/1990 - "Local cellular host response induced by Nocardia-delipidated cell mitogen in Lewis lung carcinoma-bearing mice."
09/01/1990 - "Since lymphocytes were also found around non-treated tumors and they apparently did not prevent tumor development, it is possible that macrophages play a more important role in the NDCM-elicited host defense against the Lewis lung carcinoma."
01/01/1987 - "administration of emulsified NDCM and of two other compounds, a Nocardia water soluble mitogen (NWSM a hydrosoluble fraction) and purified cell walls (CW, an insoluble macromolecular fraction) in Lewis lung carcinoma (LLC)-bearing mice resulted in a significant reduction of lung metastases. "
09/01/1990 - "With the aim of obtaining further information on the mechanism of action of these immunomodulators, we examined in the present study the local cellular host response induced by intratumoral administration of one of these fractions, the Nocardia-delipidated cell mitogen (NDCM), at the site of the tumor (Lewis lung carcinoma-3LL). "

01/01/1987 - "administration of emulsified NDCM and of two other compounds, a Nocardia water soluble mitogen (NWSM a hydrosoluble fraction) and purified cell walls (CW, an insoluble macromolecular fraction) in Lewis lung carcinoma (LLC)-bearing mice resulted in a significant reduction of lung metastases. "

02/01/2018 - "This study examined whether the serum PON1 activity is different in patients with ischaemic dilated cardiomyopathy (IDCM) and nonischaemic dilated cardiomyopathy (NDCM) and the relation between the serum PON1 activity and serum pro-BNP levels. "
12/01/2022 - "We therefore performed the first systematic review evaluating evidence on the prognostic value of CMR derived LV-GLS for ischaemic (IDCM) and non-ischaemic dilated cardiomyopathy (NDCM) patients. "
01/01/2021 - "A considerable number of non-ischemic dilated cardiomyopathy (NDCM) patients had been found to have normalized left ventricular (LV) size and systolic function with tailored medical treatments. "
10/01/2011 - "Patients in all 3 groups realized improvements in LVEF (%) after CRT as follows: NDCM (n = 137; LVEDD ≤5.5 cm) 10.0 ± 12.7, P < .001; moderately dilated cardiomyopathy (n = 233; LVEDD 5.6-6.9 cm) 8.2 ± 11.3, P < .001; and SDCM (n = 101; LVEDD ≥7.0 cm) 5.4 ± 9.4, P < .001. "
10/01/2011 - "We examined changes in left ventricular ejection fraction (LVEF) and survival in patients with NDCM or SDCM compared with those with traditionally studied moderately dilated cardiomyopathy. "

07/01/1991 - "Although the macrophage appears to be of major importance in the NDCM-induced host response against the tumor, other components of the immune system are probably system are probably also activated by the Nocardia fraction in defense against the neoplasm."
07/01/1991 - "Examination of lungs in 3LL-bearing mice treated by NDCM showed a rich infiltration of macrophages in the vicinity of isolated tumor cells, probably indicating a defensive role of NDCM-activated macrophages against metastatic spread of the tumor. "
07/01/1991 - "It is therefore possible that by delaying white pulp depletion, NDCM favors a better host defense against the tumor. "
07/01/1991 - "These results correlate with previous findings which showed a local accumulation of macrophages (but also lymphocytes) at the tumor site in NDCM-treated mice. "
07/01/1991 - "Macrophages activated by NDCM exerted a cytotoxic effect on 3LL cells in vitro, indicating a direct influence of macrophages on the tumor cells. "

04/01/2010 - "The aim of this study was to investigate the association between myocardial fibrosis and intraventricular systolic dyssynchrony (DYS-sys) in patients with NDCM. "
01/01/2011 - "Fragmentation of QRS complexes on ECG is associated with intraventricular systolic dyssynchrony and subendocardial fibrosis in NDCM patients with a narrow QRS interval and sinus rhythm."
01/01/2011 - "We investigated the association of fragmented QRS (fQRS) complexes with systolic dyssynchrony and myocardial fibrosis in patients with NDCM. "
04/01/2010 - "Patients with NDCM and prominent cardiac fibrosis have significant DYS-sys. "
04/01/2010 - "Left ventricular dyssynchrony and myocardial fibrosis are common findings in patients with nonischemic dilated cardiomyopathy (NDCM). "