|1.||Martínez, J A: 2 articles (09/2003 - 02/2000)|
|2.||Marti, A: 2 articles (09/2003 - 02/2000)|
|3.||Lamas, O: 1 article (09/2003)|
|4.||Martínez, J Alfredo: 1 article (03/2002)|
|5.||Moreno-Aliaga, María J: 1 article (03/2002)|
|6.||Marti, Amelia: 1 article (03/2002)|
|7.||Lamas, Oscar: 1 article (03/2002)|
|8.||Berraondo, B: 1 article (02/2000)|
|9.||Duncan, J S: 1 article (02/2000)|
|10.||Trayhurn, P: 1 article (02/2000)|
09/01/2003 - "The administration of trecadrine was able to prevent the onset of obesity in cafeteria-fed rats. "
02/01/2000 - "The new beta3-adrenergic agonist, Trecadrine, decreases fat content and increases gastrocnemius muscle UCP2 gene expression in a diet-induced obesity model. "
02/01/2000 - "The anti-obesity properties of a new beta3-adrenergic agonist (Trecadrine) were examined in a diet-induced obesity model, including the effects on OB and uncoupling protein (UCP-1 and -2) gene expression. "
10/30/1999 - "In conclusion, the results of this trial support that Trecadrine administration may have a therapeutic potential in disorders associated with hypertriglyceridemia such as obesity and some types of hyperlipidaemias."
02/01/2000 - "A negative correlation between WAT O2 consumption and UCP2 expression was found in control animals, but not in the cafeteria-fed groups, suggesting a differential response to the beta3-adrenergic compound in lean and obese animals, which is in agreement with the reported statistical interactions between obesity and Trecadrine administration found for WAT O2 consumption and muscle UCP2 expression, as well as for plasma leptin and WAT leptin expression. "
03/15/2002 - "In conclusion, adipocytes of diet-induced overweight animals have a higher basal leptin secretion, which is reduced by treatment with Trecadrine. "
03/15/2002 - "Plasma insulin levels were slightly elevated in overweight rats, while a decrease was observed in Trecadrine-treated groups. "
03/15/2002 - "In fact, Trecadrine treatment was able to restore to control values the impairment in insulin-mediated glucose uptake induced by the cafeteria diet, suggesting that Trecadrine prevents the development of insulin resistance in overweight animals. "