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tyrphostin AG 1478

preferentially inhibits human glioma cells expressing truncated rather than wild-type epidermal growth factor receptors
Also Known As:
4-(3-chloroanilino)-6,7-dimethoxyquinazoline; AG 1478; AG-1478; AG1478; RTKI cpd; tyrphostin AG 1478 monohydrochloride; tyrphostin AG 1478-mesylate; tyrphostin-AG1478
Networked: 149 relevant articles (9 outcomes, 19 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Halgunset, Jostein: 4 articles (05/2006 - 01/2006)
2. Skogseth, Haakon: 4 articles (05/2006 - 01/2006)
3. Larsson, Erik: 4 articles (05/2006 - 01/2006)
4. Yousif, Mariam H M: 3 articles (01/2012 - 08/2009)
5. Akhtar, Saghir: 3 articles (01/2012 - 08/2009)
6. Benter, Ibrahim F: 3 articles (01/2012 - 08/2009)
7. Xu, Ke-Ping: 3 articles (05/2007 - 03/2004)
8. Yu, Fu-Shin X: 3 articles (05/2007 - 03/2004)
9. Levitzki, A: 3 articles (05/2006 - 05/2001)
10. Ogawa, Michio: 3 articles (09/2005 - 11/2004)

Related Diseases

1. Adenocarcinoma
2. Glioma (Gliomas)
3. Demyelinating Diseases (Demyelinating Disease)
4. Neoplasms (Cancer)
5. Asthma (Bronchial Asthma)

Related Drugs and Biologics

1. Protein-Tyrosine Kinases (Tyrosine Kinase)
2. Epidermal Growth Factor (EGF)
3. GW 583340
4. lapatinib (GW572016)
5. Genistein
6. heparin-binding EGF-like growth factor (HB-EGF)
7. N- (2- cyclohexyloxy- 4- nitrophenyl)methanesulfonamide
8. temozolomide (Temodar)
9. Phosphotransferases (Kinase)
10. Cisplatin (Platino)

Related Therapies and Procedures

1. Heterologous Transplantation (Xenotransplantation)
2. Radiotherapy
3. Drug Therapy (Chemotherapy)
4. Debridement
5. Aftercare (After-Treatment)