|1.||Bautista, Diana M: 2 articles (07/2013 - 03/2010)|
|2.||Stucky, Cheryl L: 2 articles (07/2013 - 03/2010)|
|3.||Tsunozaki, Makoto: 2 articles (07/2013 - 03/2010)|
|4.||Lennertz, Richard C: 2 articles (07/2013 - 03/2010)|
|5.||Vilceanu, Daniel: 1 article (07/2013)|
|6.||Katta, Samata: 1 article (07/2013)|
|7.||Braun, Gabriella: 1 article (04/2012)|
|8.||Czirják, Gábor: 1 article (04/2012)|
|9.||Enyedi, Péter: 1 article (04/2012)|
04/28/2012 - "The active ingredient of Sichuan pepper, sanshool, has been suggested to evoke tingling paresthesia by inhibiting the channel in a mechanoreceptor subpopulation of sensory neurons. "
03/24/2010 - "Hydroxy-alpha-sanshool, the active ingredient in plants of the prickly ash plant family, induces robust tingling paresthesia by activating a subset of somatosensory neurons. "
03/24/2010 - "Physiological basis of tingling paresthesia evoked by hydroxy-alpha-sanshool."
03/24/2010 - "The identification of sanshool-sensitive fibers represents an essential first step in identifying the cellular and molecular mechanisms underlying tingling paresthesia that accompanies peripheral neuropathy and injury."
|3.||Peripheral Nervous System Diseases (PNS Diseases)
07/01/2013 - "To elucidate the molecular mechanisms by which sanshool attenuates mechanical pain, we performed single fibre recordings, calcium imaging and whole-cell electrophysiology of cultured sensory neurons. "
07/01/2013 - "These results suggest that sanshool targets voltage-gated sodium channels on Aδ mechanosensory nociceptors to dampen excitability and thus induce 'fast pain' analgesia."
07/01/2013 - "We found that: (1) sanshool potently inhibits Aδ mechanonociceptors that mediate both sharp acute pain and inflammatory pain; (2) sanshool inhibits action potential firing by blocking voltage-gated sodium currents in a subset of somatosensory neurons, which express a unique combination of voltage-gated sodium channels; and (3) heterologously expressed Nav1.7 is most strongly inhibited by sanshool as compared to other sodium channels expressed in sensory neurons. "
|1.||Sodium Channels (Sodium Channel)