|1.||Lomas, David A: 29 articles (11/2013 - 05/2002)|
|2.||Miranda, Elena: 14 articles (01/2015 - 03/2004)|
|3.||Crowther, Damian C: 14 articles (11/2013 - 05/2002)|
|4.||Belorgey, Didier: 13 articles (10/2011 - 05/2002)|
|5.||Marciniak, Stefan J: 8 articles (11/2013 - 06/2009)|
|6.||Lawrence, Daniel A: 6 articles (07/2015 - 06/2002)|
|7.||Roussel, Benoit D: 6 articles (11/2013 - 07/2009)|
|8.||Pérez, Juan: 6 articles (03/2011 - 06/2008)|
|9.||Onda, Maki: 6 articles (11/2010 - 08/2004)|
|10.||Yepes, Manuel: 6 articles (11/2010 - 06/2002)|
|1.||Alzheimer Disease (Alzheimer's Disease)
05/01/2015 - "Familial encephalopathy with neuroserpin inclusions bodies (FENIB) is a serpinopathy that induces a rare form of presenile dementia. "
11/01/2013 - "Alzheimer's disease brain tissues with elevated neuroserpin protein also showed increased expression of THRβ1 and HuD. "
11/01/2013 - "A series of Alzheimer's disease brain tissues were compared to age-matched control brains for their expression of neuroserpin, THRβ1 and HuD by western blotting. "
12/01/2000 - "Mutations in the Neuroserpin gene have been reported to cause familial presenile dementia. "
09/29/2006 - "Neuroserpin binds Abeta and is a neuroprotective component of amyloid plaques in Alzheimer disease."
01/01/2007 - "This study provides the first evidence that neuroserpin is associated with early-onset ischemic stroke among Caucasian women."
01/01/2007 - "Neuroserpin single nucleotide polymorphisms (SNPs) chosen through HapMap were genotyped in the study population and assessed for association with stroke. "
01/01/2007 - "Neuroserpin polymorphisms and stroke risk in a biracial population: the stroke prevention in young women study."
07/15/2000 - "In the present study neuroserpin expression and its potential therapeutic benefits were examined in a rat model of stroke. "
01/01/2013 - "To examine neuroserpin-dependent mechanisms of neuroprotection in stroke, we studied neuroserpin deficient (Ns(-/-))mice in an animal model of temporal focal ischemic stroke. "
01/01/2010 - "Finally we outline the varied paradigms that have been employed in the study of the serpinopathies, and in particular, a dementia caused by neuroserpin polymerization."
03/01/2011 - "Point mutations in the neuroserpin gene cause the autosomal dominant dementia familial encephalopathy with neuroserpin inclusion bodies or FENIB. "
01/01/2011 - "These inclusions underlie the autosomal dominant dementia familial encephalopathy with neuroserpin inclusion bodies or FENIB. "
02/01/2010 - "Point mutations in the neuroserpin gene underlie the autosomal dominant dementia, familial encephalopathy with neuroserpin inclusion bodies. "
08/21/2009 - "They are a diverse group including alpha(1)-antitrypsin deficiency and the inherited dementia familial encephalopathy with neuroserpin inclusion bodies or FENIB. "
02/01/2011 - "Our results suggest that neuroprotective activity of neuroserpin involves attenuation on tPA-mediated mechanisms of inflammation and BBB disruption after brain ischemia."
01/01/2011 - "These findings suggest that neuroprotective properties of neuroserpin may be related to the inhibition of excitotoxicity, inflammation, as well as blood brain barrier disruption that occur after acute ischemic stroke."
01/01/2011 - "Our aim was to study whether neuroserpin serum levels could be associated to biomarkers of excitotoxicity, inflammation and blood brain barrier disruption. "
01/01/2013 - "Deficiency in serine protease inhibitor neuroserpin exacerbates ischemic brain injury by increased postischemic inflammation."
01/01/2011 - "Serine Protease inhibitors (Serpins) like antithrombin, antitrypsin, neuroserpin, antichymotrypsin, protein C-inhibitor and plasminogen activator inhibitor is involved in important biological functions like blood coagulation, fibrinolysis, inflammation, cell migration and complement activation. "
|5.||Progressive Myoclonic Epilepsies (Progressive Myoclonic Epilepsy)
12/01/2000 - "Our study characterizes for the first time the neuropathologic phenotype associated with hereditary progressive myoclonus epilepsy caused by the S52R Neuroserpin mutation."
09/01/2011 - "Encephalopathy with neuroserpin inclusion bodies presenting as progressive myoclonus epilepsy and associated with a novel mutation in the Proteinase Inhibitor 12 gene."
07/03/2007 - "In a French family with the S52R mutation of the neuroserpin gene, progressive myoclonic epilepsy was associated with a frontal syndrome. "
04/07/2004 - "Mutations in the neuroserpin gene cause protein polymerization and formation of inclusion bodies leading to progressive myoclonic epilepsy and neurodegeneration. "
12/01/2000 - "We describe a new family in which the S52R Neuroserpin mutation is associated with progressive myoclonus epilepsy in 2 siblings. "
|1.||Tissue Plasminogen Activator (Alteplase)
|3.||Amyloid (Amyloid Fibrils)
|4.||Biological Markers (Surrogate Marker)
|6.||Familial encephalopathy with neuroserpin inclusion bodies
|7.||Serine Proteases (Serine Protease)
|9.||Messenger RNA (mRNA)
|10.||Plasminogen Activators (Plasminogen Activator)