norgestomet

synthetic 19-norprogesterone that synchronizes estrus in cattle without reducing fertility; affects pituitary gonadotropins & the menstrual cycle in humans; minor descriptor (79-86), on-line & INDEX MEDICUS search PREGNENEDIONES (79-86); RN given refers to (11beta)-isomer

Also Known As:

Networked: 7 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Related Diseases

1.	Body Weight (Weight, Body) 03/01/1992 - "Heifers with Norgestomet implants had higher body weight gains during the last 66 days (P < 0.05), and during the entire 122-day trial (P < 0.07) than heifers with placebo implants. " 03/01/1999 - "Based on a per-kg-body-weight basis, the norgestomet-treated bull is the most sensitive biological assay model." 12/01/1995 - "Effects of body weight, condition score, ovarian cyclic status and insemination regimen on pregnancy rates were investigated in 164 Bos indicus heifers synchronised with norgestomet-oestradiol and pregnant mare serum gonadotrophin (PMSG). "
2.	Weight Gain 12/01/1997 - "These data indicate that norgestomet implants increased rate of weight gain, reduced estrous activity, and reduced the occurrence of pregnancy in heifers on pasture." 03/01/1992 - "The Norgestomet implant has the potential for suppressing ovarian luteal activity while improving weight gain in beef heifers." 03/01/1992 - "A 122-day trial was conducted with grazing beef heifers (N=120; 14 to 17 months of age) to determine the effects of a silastic Norgestomet prototype implant on heifer weight gain and on the suppression of ovarian luteal activity. "
3.	Flushing 05/01/1998 - "The effects of energy supplementation (flushing) on LH and estradiol secretion, follicular growth and the response to estrus synchronization treatment (Norgestomet + PMSG initiated 41.9 +/- 3.4 d after calving) were investigated in 16 suckled beef cows fed either 70% (Group C, n = 8) of energy requirements from calving to 3 wk after AI or fed the same restricted diet until 11 d before synchronization and then were supplemented with 2 kg concentrate until 3 wk after AI (Group S, n = 8). "
4.	Dystocia 07/01/1997 - "Dystocia (P < 0.05), retention of fetal membranes (P < 0.01), and calf mortality (P < 0.01) were higher for the ovariectomized heifers with norgestomet implants than for the control heifers."
5.	Breast Neoplasms (Breast Cancer) 01/01/1993 - "In MCF-7 breast cancer cell bioassays, norgestomet showed weak estrogenic activity, but only at concentrations greater than 1 micromolar. "

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