carbuterol

sympathomimetric specific for beta2 receptors; proposed bronchodilator agent; minor descriptor (78-86); on-line & INDEX MEDICUS search ETHANOLAMINES (78-86); RN given refers to parent cpd

Also Known As:

(5-(2-(tert-butylamino)-1-hydroxyethyl)-2-hydroxyphenyl)urea; SK&F 40,383-A; SK&F 40383; SK&F-40,383-A; SK&F-40383; SKF 40383-A; carbuterol monohydrochloride; carbuterol monohydrochloride, (+)-isomer; carbuterol monohydrochloride, (-)-isomer

Networked: 15 relevant articles (2 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Amino Alcohols: 20
    - Ethanolamines: 16
      - carbuterol: 15
- Alcohols: 595
  - Ethanol: 23169
    - Ethanolamines: 16
      - carbuterol: 15
  - Amino Alcohols: 20
    - Ethanolamines: 16
      - carbuterol: 15

Related Diseases

1.	Asthma (Bronchial Asthma) 07/01/1977 - "Double-blind trial of oral carbuterol in bronchial asthma." 01/01/1981 - "Thus, carbuterol is an effective and safe selective beta 2-adrenergic stimulant, is relatively free from side-effects, and has a sustained bronchodilator effect, an advantage in therapeutic application, and is, as a result, a new effective drug in the management of bronchial asthma." 01/01/1981 - "Double-blind crossover study of carbuterol and salbutamol in bronchial asthma." 08/01/1979 - "The bronchodilator efficacy of oral carbuterol in the dose of 2 mg or 3 mg was compared with that of 4 mg salbutamol in a double-blind, crossover trial in 21 patients with bronchial asthma. " 06/28/1980 - "A comparison of carbuterol, fenoterol and hexoprenaline in allergic asthma."
2.	Exercise-Induced Asthma (Asthma, Exercise Induced) 11/01/1985 - "We decided in this work to evaluate the prophylactic value of carbuterol in exercise-induced asthma (EIA), comparing this drug to salbutamol and DSCG in order to describe its usefulness in exercise-induced asthma, while employing the closing-pressure method for the early detection of airway constriction. " 11/01/1985 - "Carbuterol, salbutamol and DSCG in exercise-induced asthma." 06/17/1978 - "The aerosols of carbuterol (200 mg) and fenoterol (400 mg) appeared to be similar in inhibiting exercise-induced asthma, whereas hexoprenaline (200 mg) did not appear to be as effective."
3.	Airway Obstruction (Choking) 03/01/1976 - "A new oral bronchodilator, carbuterol, was studied in 9 subjects who had reversible airway obstruction. " 01/01/1981 - "A double-blind crossover comparative study between carbuterol 3 mg thrice daily, carbuterol 2 mg thrice daily and salbutamol 4 mg thrice daily by the oral route was conducted in thirty patients suffering from bronchial asthma, selected at random, with more than 20% reduction in airway obstruction following isoprenaline inhalation. "
4.	Chronic Bronchitis 05/01/1983 - "[Effect of carbuterol and of a fenoterol-ipratropium bromide combination on mucociliary transport in chronic bronchitis]."
5.	Chronic Obstructive Pulmonary Disease (COPD) 12/01/1981 - "Comparison of the bronchodilator effects of aerosol carbuterol and isoproterenol in chronic obstructive lung disease."

Related Drugs and Biologics

1.	Bronchodilator Agents (Bronchodilators)
2.	Albuterol (Salbutamol)
3.	Aerosols
4.	Hexoprenaline
5.	Isoproterenol (Isoprenaline)
6.	Fenoterol
7.	Ephedrine
8.	ipratropium drug combination fenoterol
9.	Adrenergic Agents (Adrenergic Drugs)
10.	Sympathomimetics (Sympathomimetic Amines)