bromebric acid (11-1933)

major descriptor (74-86); on line search ACRYLATES (74-86); INDEX MEDICUS search BROMEBRIC ACID (74-86); RN given refers to parent cpd

Also Known As:

11-1933; Cytembena; Mebryl; bromebric acid, (E)-isomer; bromebric acid, sodium salt; bromebric acid, sodium salt, (E)-isomer; bromebric acid, sodium salt, (Z)-isomer; (E)-3-p-anisoyl-3-bromoacrylic acid

Networked: 37 relevant articles (0 outcomes, 4 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Carboxylic Acids: 973
  - Acyclic Acids
    - Acrylates: 212
      - bromebric acid: 37

Related Diseases

1.	Carcinoma (Carcinomatosis) 12/01/1977 - "In a phase II clinical (screening) trial, Cytembena has induced 20% objective regressions in uterus cervix carcinoma. " 01/01/1971 - "Cytembena treatment of advances and relapsing uterine cervix carcinoma." 01/01/1971 - "Cytembena treatment of advanced gynaecological carcinomas." 01/01/1982 - "Cytembena and cis-platinum in combination for advanced stage ovarian carcinoma treatment." 12/01/1977 - "Seventeen patients with stages III and IV alkylating agent-resistant ovarian carcinomas were treated with cytembena, which was given in doses of 200 mg/m2 twice daily for 5 consecutive days every 5 weeks. "
2.	Breast Neoplasms (Breast Cancer) 11/01/1976 - "Phase II trial of cytembena in patients with advanced ovarian and breast cancer." 11/01/1976 - "Thirty women with histologically proven advanced ovarian or breast cancer were treated with cytembena. " 05/01/1976 - "Phase II evaluation of VP-16-213 (NSC-141540) and cytembena (NSC-104801) in patients with advanced breast cancer."
3.	Colorectal Neoplasms (Colorectal Cancer) 05/01/1975 - "Phase II study of cytembena (NSC-104801) in advanced colorectal carcinoma."
4.	Asthma (Bronchial Asthma) 07/01/1963 - "A CONTROLLED TRIAL OF A NEW ANTIHISTAMINIC (MEBROPHENHYDRAMINE, "MEBRYL") IN THE TREATMENT OF ASTHMA."
5.	Neoplasms (Cancer) 11/01/1976 - "Five patients with various types of malignancy, so far medically untreated, received 20 mg Cytembena/kg body wt i.v. A combination of Cytembena and cylophosphamide was applied i.p. " 01/01/1975 - "In patients with malignant tumors, changes in the blood count and morphological changes in the nucleoli in peripheral-blood lymphocytes were studied during treatment with Cytembena, Cyclophosphamide, or combinations of both drugs. " 01/01/1975 - "The effects of combined administration of cytembena and cyclophosphamide on the blood count and morphology of nucleoli in peripheral-blood lymphocytes in patients with malignant tumors." 07/01/1974 - "[Cytembena and cyclophosphamide in the treatment of advanced neoplasias of the digestive tract (author's transl)]." 08/01/1973 - "[Some clinical data on the state of patients with inoperable cancer of the internal sex organs treated with cytembena and cyclophosphamide preparations]."

Related Drugs and Biologics

1.	embramine
2.	Cyclophosphamide (Cytoxan)
3.	Cytostatic Agents
4.	Cisplatin (Platino)
5.	thyminalkylamine
6.	Therapeutic Uses
7.	Vincristine (Oncovin)
8.	Sulfhydryl Compounds (Thiols)
9.	Solutions
10.	L-Lactate Dehydrogenase (Lactate Dehydrogenase)

Related Therapies and Procedures

1.	Therapeutics
2.	Combination Drug Therapy (Combination Chemotherapy)
3.	Drug Therapy (Chemotherapy)
4.	Aftercare (After-Treatment)
5.	Contraindications