|1.||Magni, E: 1 article (03/2010)|
|2.||Pace, F: 1 article (03/2010)|
|3.||Ciacci, C: 1 article (03/2010)|
|4.||Maurano, A: 1 article (03/2010)|
|5.||Porro, G Bianchi: 1 article (03/2010)|
|6.||Iaquinto, G: 1 article (03/2010)|
|7.||Attili, A: 1 article (03/2010)|
|8.||Savarino, V: 1 article (03/2010)|
11/01/1966 - "Anisotropine methylbromide for relief of gastrointestinal spasm: double-blind crossover comparison study with belladonna alkaloids and phenobarbital."
12/22/1970 - "[Anisotropine methylbromide (Valpin) in the treatment of spasms of the gastrointestinal system. "
04/01/1972 - "Effects of anisotropine methylbromide (Valpin) and its mixture with sulpyrine on vocalization response and spasm of intestine induced by acetylcholine in dogs."
|2.||Muscle Spasticity (Spastic)
05/01/1973 - "[Clinical study of the selectivity, tolerance and therapeutic status of anisotropine methylbromide and its combinations (Vapin Complex) in digestive pathology and in spastic changes of the biliary tract]."
09/30/1982 - "[Effectiveness of octatropine methylbromide (OMB) in the treatment of gastritis, duodenal ulcer and spastic colon--a double blind study]."
|3.||Irritable Bowel Syndrome (Syndrome, Irritable Bowel)
03/01/2010 - "Octatropine methyl bromide and diazepam combination (Valpinax) in patients with irritable bowel syndrome: a multicentre, randomized, placebo-controlled trial."
03/01/2010 - "To investigate the efficacy and tolerability of octatropine methyl bromide plus diazepam (Valpinax) in patients with irritable bowel syndrome (IBS). "
|4.||Duodenal Ulcer (Curling's Ulcer)
|5.||Abdominal Pain (Pain, Abdominal)
03/01/2010 - "Patients with IBS and an abdominal pain and discomfort score of > or = 3, who may be considered in the active phase of the disease, may derive some benefits from octatropine plus diazepam. "
03/01/2010 - "A prespecified subgroup analysis was conducted in patients with an abdominal pain and discomfort score > or = 3. The primary efficacy endpoint showed a tendency towards a statistically significant benefit for octatropine plus diazepam over placebo among patients with a baseline abdominal pain and discomfort score of > or = 3 (3 vs. 0 patients; p = 0.059). "
|1.||methyl bromide (bromomethane)
|6.||octotropine methylbromide (anisotropine methylbromide)
|8.||Acetylcholine (Acetylcholine Chloride)