luteoskyrin

mycotoxin from Penicillium islandicum; pollutant of stored rice; minor descriptor (75-85); on-line & Index Medicus search NAPHTHOQUINONES (75-85); RN given refers to (1S,1'S,2R,2'R,3S,3'S,9aR,9'aR)-isomer

Networked: 10 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Polycyclic Aromatic Hydrocarbons: 2020
        Naphthalenes: 18
        Naphthoquinones: 418
        luteoskyrin: 10
- Quinones: 434
  - Naphthoquinones: 418
    - luteoskyrin: 10
Polycyclic Compounds: 6
- Polycyclic Aromatic Hydrocarbons: 2020
  - Naphthalenes: 18
    - Naphthoquinones: 418
      - luteoskyrin: 10

Experts

1.	Choudhury, Sujata Maiti: 1 article (01/2010)
2.	Gupta, Malaya: 1 article (01/2010)
3.	Majumder, Upal Kanti: 1 article (01/2010)

Related Diseases

1.	Neoplasms (Cancer) 12/01/1966 - "Biochemical and histopathological studies on the tumor-developing livers of mice fed on the diets containing luteoskyrin."
2.	Hepatocellular Carcinoma (Hepatoma) 01/01/1985 - "Among experimental models of liver cancer produced by a large number of agents, only carbon tetrachloride and luteoskyrin seem to induce liver cell carcinoma combined with cirrhotic lesions in rodents. " 04/01/1992 - "When cultured Reuber hepatoma H4-II-E and fibroblast Balb/3T3 cells were exposed to various concentrations of 5 derivatives of anthraquinones, luteoskyrin, a bis-anthraquinoid hepatocarcinogenic mycotoxin, exhibited the highest cytotoxicity to these cell lines. "
3.	Ehrlich Tumor Carcinoma 01/01/2010 - "Luteoskyrin,a hydroxyanthraquinone has been proved to be a potent inhibitor against Ehrlich ascites tumor cells. " 09/01/1969 - "Inhibition of DNA synthesis and chromosome aberrations in cultured ehrlich ascites tumor cells following treatment with luteoskyrin."
4.	Chromosome Breakage 01/01/1969 - "Induction of chromosomal breakage in cultured human leucocytes by luteoskyrin."
5.	Wounds and Injuries (Trauma) 07/01/1995 - "From these results we proposed that luteoskyrin liver injuries are induced by the active oxygen species generated in the process of autoxidation of luteoskyrin semiquinone radical which is produced in the one-electron redox systems catalyzed by the liver NAD(P)H-dependent cytochrome reductases."

Related Drugs and Biologics

1.	Reactive Oxygen Species (Oxygen Radicals)
2.	RNA (Ribonucleic Acid)
3.	NAD (NADH)
4.	Mycotoxins
5.	DNA (Deoxyribonucleic Acid)
6.	Cytochrome Reductases
7.	Carbon Tetrachloride (Tetrachloromethane)
8.	Anthraquinones