statolon (vistatolon)

polyanionic polysaccharide from Penicillium stoloniferum; induces interferon; used as antiviral agent & proposed as antineoplastic agent; minor descriptor (69-72); major descriptor (73-85); on-line search POLYSACCHARIDES (69-85); Index Medicus search POLYSACCHARIDES (69-72); STATOLON (73-85)

Also Known As:

Networked: 34 relevant articles (2 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Related Diseases

1.	Leukemia 03/01/1975 - "Impaired macrophage function in Friend virus leukemia: restoration by statolon." 07/01/1973 - "Suppression of established Friend virus leukemia by statolon. " 02/01/1973 - "Suppression of established Friend virus leukemia by statolon. " 03/01/1972 - "Suppression of established Friend virus leukemia by statolon. " 04/01/1971 - "Suppression of established Friend virus leukemia by statolon. "
2.	Virus Diseases (Viral Diseases) 06/01/1972 - "Protection of newborn mice during neonatal immunological unresponsiveness from a lethal virus infection by injection of statolon." 07/01/1969 - "A single inoculation of statolon into mice with established Friend virus (FV) leukemia can suppress the viral infection and produce a clinical remission lasting many months. " 05/01/1967 - "No therapeutic effect was observed when treatment with statolon was delayed for 2 days or more after virus infection. " 01/01/1969 - "Effect of statolon on acute and persistent murine leukemia and sarcoma virus infections."
3.	Human Influenza (Influenza) 08/01/1969 - "Mice were treated intraperitoneally with statolon and challenged with influenza A(2) virus by the intranasal route. " 08/01/1969 - "Influence of statolon on resistance of mice to influenza." 08/01/1969 - "Because of the relatively high morbidity rate of influenza and its seasonal occurrence, we wished to determine whether statolon-induced interferon might be effective in controlling this disease. "
4.	Carcinogenesis 07/01/1972 - "Study on the effect of statolon on methylcholanthrene oncogenesis in mice."
5.	Infections 01/01/1970 - "Effect of statolon on lactate dehydrogenase virus infection in mice." 03/01/1968 - "Mice which received statolon 1 to 5 days before infection were significantly more resistant to the virus than nontreated controls; no protection could be demonstrated in the other groups." 09/01/1967 - "Treatment of mengovirus infection in mice with statolon." 05/01/1967 - "Exposure of mice to a simulated space cabin environment did not increase their susceptibility to the lethal effects of mengovirus infection or eliminate the protective effect of statolon." 01/01/1986 - "We have been studying a murine model in which a rapidly fatal FLV infection of DBA/2 mice is suppressed to a dormant state by treatment with statolon, a double stranded RNA extract of Mycoplasma stoloniferum. "

Related Drugs and Biologics

1.	Interferons
2.	Methylcholanthrene
3.	Tilorone (Tilorone Hydrochloride)
4.	Poly I-C
5.	Interferon Inducers
6.	Pyran Copolymer
7.	oxyamylose (COAM)
8.	Therapeutic Uses
9.	Silicon Dioxide (Silica)
10.	Double-Stranded RNA (RNA, Double Stranded)

Related Therapies and Procedures

1.	Therapeutics
2.	Life Support Care
3.	Intraperitoneal Injections