|1.||Liu, Shuang: 12 articles (09/2013 - 11/2005)|
|2.||Kim, Young-Seung: 8 articles (03/2012 - 11/2005)|
|3.||Wang, Fan: 7 articles (10/2013 - 07/2006)|
|4.||Chen, Xiaoyuan: 5 articles (10/2013 - 03/2007)|
|5.||Shi, Jiyun: 5 articles (10/2011 - 07/2006)|
|6.||Jia, Bing: 5 articles (08/2009 - 07/2006)|
|7.||Shafiei, Mohammad: 4 articles (03/2014 - 08/2007)|
|8.||Zhou, Yang: 4 articles (09/2013 - 10/2011)|
|9.||Hsieh, Wen-Yuan: 4 articles (01/2008 - 11/2005)|
|10.||Erfani, Mostafa: 3 articles (01/2015 - 04/2013)|
01/01/2015 - "Tumor-to-muscle ratio was found to reach to the highest (4.17±0.49) at 2 hour after intravenously administration of [99mTc]-(HYNIC-AF7P)(tricine)(TPPTS) into MDA-MB-231 tumor bearing mice. "
09/03/2013 - "Its lower uptake in intestines, lungs, and spleen suggests that (99m)Tc-Galacto-RGD2 has advantages over (99m)Tc-3P-RGD2 ([(99m)Tc(HYNIC-3P-RGD2)(tricine)(TPPTS)]: 3P-RGD2 = PEG4-E[PEG4-c(RGDfK)]2; PEG4 = 15-amino-4,7,10,13-tetraoxapentadecanoic acid) for imaging tumors in the chest and abdominal regions. "
01/01/2008 - "Among the three radiotracers evaluated in this tumor-bearing animal model, [(99m)Tc(HYNIC tetramer)(tricine)(TPPTS)] remained the best with respect to blood clearance, tumor uptake and target/background ratios."
03/01/2007 - "SPECT images displayed significant radiotracer localization in tumor with good contrast as early as 1 h p.i. The high tumor uptake and fast renal excretion make [99mTc(HYNIC-tetramer)(tricine)(TPPTS)] a promising radiotracer for noninvasive imaging of the integrin alphavbeta3-positive tumors by SPECT."
03/01/2007 - "The metabolic stability of [99mTc(HYNIC-tetramer)(tricine)(TPPTS)] was determined by analyzing urine and feces samples from the tumor-bearing mice at 120 min p.i. In the urine, about 20% of [99mTc(HYNIC-tetramer)(tricine)(TPPTS)] remained intact while only approximately 15% metabolized species was detected in feces. "
12/01/2014 - "Tc-EDDA-tricine-HYNIC-Tyr-octreotate scintigraphy may help to differentiate between active and inactive pulmonary tuberculosis. "
12/01/2014 - "The current study was performed to evaluate the impact of Tc-EDDA-tricine-HYNIC-Tyr-octreotate in the differentiation of active from inactive pulmonary tuberculosis lesions. "
|3.||Prostatic Neoplasms (Prostate Cancer)
10/01/2013 - "Application of (99m)Technetium-HYNIC(tricine/TPPTS)-Aca-Bombesin(7-14) SPECT/CT in prostate cancer patients: a first-in-man study."
10/01/2013 - "We used the BBN-based radiopharmaceutical (99m)Technetium-HYNIC(tricine/TPPTS)-Aca-Bombesin(7-14) ((99m)Tc-HABBN) to perform a first-in-man clinical pilot study to evaluate the feasibility of (99m)Tc-HABBN SPECT/CT for detection of prostate cancer in patients. "
08/01/2011 - "We have synthesized a new BN-based radiopharmaceutical (99m)technetium-HYNIC(tricine/TPPTS)-Aca-BN(7-14) ((99m)Tc-HABN) and evaluated its GRPR targeting properties in vitro and in a xenograft tumor model for human prostate cancer in athymic mice. "
08/01/2011 - "(99m)technetium-HYNIC(tricine/TPPTS)-Aca-bombesin(7-14) as a targeted imaging agent with microSPECT in a PC-3 prostate cancer xenograft model."
02/01/2009 - "This study was conducted to evaluate the potentiality of [(99m)Tc/Tricine/HYNIC(0)]UBI 29-41 prepared from lyophilized kits as an infection imaging agent in humans. "
02/01/2009 - "Images showed minimal accumulation in nontarget tissues, with an average target/nontarget ratio of 2.10+/-0.33 in positive lesions at 30 min. Given its favorable clinical characteristics, [(99m)Tc/Tricine/HYNIC]UBI 29-41 shows promise as a tracer for infection imaging that allows early diagnosis (30 min) of infection."
02/01/2009 - "Clinical evaluation of antimicrobial peptide [(99m)Tc/Tricine/HYNIC(0)]ubiquicidin 29-41 as a human-specific infection imaging agent."
03/01/2002 - "The most optimal infection imaging characteristics were found for formulations using nicotinic acid/tricine as coligand system combining a high specific activity and high in vitro stability with high abscess/muscle ratios (>200) and high abscess/background ratios (>20). "
|2.||Proteins (Proteins, Gene)
|3.||Integrin beta3 (GPIIIa)
|5.||Carrier Proteins (Binding Protein)
|6.||Somatostatin Receptors (Somatostatin Receptor)
|8.||ethylenediamine (ethylenediamine dihydroiodide)
|10.||Technetium (Technetium 99m)
|1.||Heterologous Transplantation (Xenotransplantation)