glisoxepide

oral sulfonylurea hypoglycemic agent which stimulates insulin secretion; minor descriptor (75-85); on-line & Index Medicus search SULFONYLUREA COMPOUNDS (75-85); RN given refers to parent cpd

Also Known As:

4-(4-beta-(5-methylisoxazol-3-carboxamidoethyl)phenylsulfonyl)-1,1-hexamethylenesemicarbazide; BS 4231; BS-4231; Pro-diaban; RP 22410; RP-22410; glisoxepid

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amides: 2428
  - Urea: 15015
    - Sulfonylurea Compounds: 35
      - glisoxepide: 4
- Sulfur Compounds: 278
  - Sulfones: 534
    - Sulfonylurea Compounds: 35
      - glisoxepide: 4

Experts

1.	Chandra, Anshuman: 1 article (01/2021)
2.	Gurjar, Vaishali: 1 article (01/2021)
3.	Qamar, Imteyaz: 1 article (01/2021)
4.	Singh, Nagendra: 1 article (01/2021)

Related Diseases

1.	Leukemia 01/01/2021 - "Two drugs Glisoxepide and Idarubicin used for treatment for diabetes and leukemia, respectively, were selected as stronger binder of EndoU. "
2.	Hypoglycemia (Reactive Hypoglycemia) 07/01/1976 - "Treatment with tolbutamide (200 mg/kg), glibenclamide (2 mg/kg) and glisoxepide (2 mg/kg), causing moderate hypoglycemia and B-cell degranulation, was associated with an unchanged (30, 90 min) or slightly increased (180, 360 min, 4, 42d) GGHA staining intensity of the islet cells compared with controls. "
3.	Hypersensitivity (Allergy) 04/06/1979 - "Typical signs and symptoms of type III allergy occurred in a 55-year-old diabetic during diabetes and diuretic treatment with glisoxepid, glibenclamide, furosemide and probenecid. "
4.	Hepatocellular Carcinoma (Hepatoma) 03/31/1992 - "Whereas glisoxepide was slowly taken up into AS-30D hepatoma cells, glibenclamide was not. "

Related Drugs and Biologics

1.	Glyburide (Glibenclamide)
2.	Idarubicin (4 Demethoxydaunorubicin)
3.	Tolbutamide (Orinase)
4.	Probenecid (Benemid)
5.	Furosemide (Lasix)
6.	Diuretics
7.	Uridylate-Specific Endoribonucleases