sintamil

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4 relevant articles (0 outcomes, 0 trials/studies) found for this Bio-Agent

Description: has pronounced sedative properties, but otherwise resembles imipramine; minor descriptor (77-84); on-line & Index Medicus search DIBENZOXAZEPINES (77-84); RN given refers to mono-HCl

Also Known As:

10-(3-(dimethylamino)propyl)-2-nitrodibenz(b,f)(1,4)-oxazepin-11(10H)-one; 233-Go; 2330 Go; nitroxazepine

Bio-Agent Context: Research Results

Heterocyclic Compounds: 23

3-Ring Heterocyclic Compounds

Dibenzoxazepines

sintamil: 4

Related Diseases

1.	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 01/01/1988 - "Modulation of sensitivity to mitoxantrone in human chronic myeloid leukemia cells by the antidepressant sintamil." 10/31/1986 - "The in vitro effect of sintamil, as a modulator alone and in combination with hydroxyurea (HU), on cytotoxicity was studied in 16 cases of human chronic myeloid leukemia (CML)" 10/31/1986 - "Augmentation of hydroxyurea cytotoxicity by sintamil in human chronic myeloid leukemia cells." Get all the results and reference details, order at left...
2.	Neoplasms (Cancer) 01/01/1987 - "The implications of the present investigations are promising, leaving hope for the utility of nitroxazepine hydrochloride in restoring drug sensitivity in adriamycin-resistant tumors." Get all the results and reference details, order at left...
3.	Leukemia 01/01/1987 - "Attempts were made to reverse the acquired resistance of P388 murine leukemia utilizing non-toxic concentration of nitroxazepine hydrochloride, an antidepressant" 01/01/1987 - "The survival of mice bearing adriamycin-resistant P388 murine leukemia cells treated in vitro with nitroxazepine hydrochloride, adriamycin and a combination of the two drugs was also investigated" 01/01/1987 - "Restoration of drug sensitivity by nitroxazepine hydrochloride in P388 murine leukemia cells resistant to adriamycin." 01/01/1987 - "The results show that treatment of these cells with nitroxazepine hydrochloride significantly enhanced (1) the intracellular accumulation of adriamycin, (2) inhibition of DNA biosynthesis, and (3) the survival of mice transplanted with adriamycin-resistant P388 murine leukemia cells treated in vitro with a combination of nitroxazepine hydrochloride and adriamycin" Get all the results and reference details, order at left...
4.	Hepatitis 04/01/1986 - "Hepatitis following nitroxazepine therapy." Get all the results and reference details, order at left...
4 Diseases and 4 more articles analyzed in the Research Interface, order at left...

Related Drugs and Biologics

1.	Mitoxantrone (Novantrone)
2.	Hydroxyurea (Hydrea)
3.	Doxorubicin (Adriamycin)
4.	DNA (Deoxyribonucleic Acid)
4 Drugs and Important Bio-Agents and 3 more articles analyzed in the Research Interface, order at left...

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