pramiverine

long acting cholinolytic proposed for gastrointestinal spasms; minor descriptor (78-84); on-line & Index Medicus search CYCLOHEXYLAMINES (78-84); RN given refers to parent cpd

Also Known As:

EMD 9806; HCl of pramiverine; HSP 2986; N-isopropyl-4,4-diphenyl cyclohexylamine; propaminodiphen; sistalgin

Networked: 7 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Cyclohexylamines: 33
    - pramiverine: 7
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Alicyclic Hydrocarbons: 1
      - Cycloparaffins: 6
        Cyclohexanes: 3
        Cyclohexylamines: 33
        pramiverine: 7

Related Diseases

1.	Lithiasis 04/01/1976 - "The authors refer to a previous trial with the combination 4,4-diphenyl-N-isopropyl-cyclohexylamine-hydrochloride (pramiverine Sistalgin) and N-methyl-N-(2,3-dimethyl-5-oxo-1-phenyl-3-pyrazolin-4-yl)-aminomethanesulfonate (metamizole) (Sistalgin comp.) in patients with renoureteral lithiasis and report results obtained with the same spasmoanalgesic and a comparative preparation in patients with biliary colics. "
2.	Pain (Aches) 04/01/1976 - "[The effect of the combination pramiverine/metamizole in colic pain (author's transl)]." 04/01/1976 - "Both judgments confirmed the rapid onset, long duration and reliable effect of pramiverine/metamizole in treating colics of the intestinal, biliary and urinary tracts as well as recurrent spastic pain. " 04/01/1976 - "A combination of 4,4-diphenyl-N-isopropyl-cyclohexylamine-hydrochloride (pramiverine, Sistalgin) and N-methyl-N-(2,3-dimethyl-5-oxo-1-phenyl-3-pyrazolin-4-yl)-aminomethanesulfonate (metamizole) (Sistalgin comp.) was injected in 250 patients with severe colic pain. "
3.	Ulcer 06/01/1972 - "Effects of the spasmolytic and anticholinergic N-isopropyl-4,4-diphenylcyclohexylamine--HCl (HSp 2986) on experimental ulcer in rats."
4.	Stomach Ulcer (Gastric Ulcer) 04/01/1976 - "A preventive effect of 4,4-diphenyl-N-isopropyl-cyclohexylamine-hydrochloride (pramiverine, Sistalgin) was determined on the experimental gastric ulcer in rats. "
5.	Muscle Spasticity (Spastic) 04/01/1976 - "Both judgments confirmed the rapid onset, long duration and reliable effect of pramiverine/metamizole in treating colics of the intestinal, biliary and urinary tracts as well as recurrent spastic pain. "

Related Drugs and Biologics

1.	pramiverine
2.	Dipyrone (Metamizole)
3.	Parasympatholytics (Antispasmodics)
4.	Cholinergic Antagonists (Anticholinergics)
5.	Scopolamine (Hyoscine)
6.	Butylscopolammonium Bromide (Butylscopolamine)
7.	Atropine
8.	butyl bromide

Related Therapies and Procedures

1.	Vagotomy