phensuximide

major descriptor (73-84); on-line search SUCCINIMIDES (73-84); Index Medicus search PHENSUXIMIDE (73-84); RN given refers to cpd without isomeric designation

Also Known As:

Networked: 6 relevant articles (2 outcomes, 0 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1.	Li, Hongjun: 1 article (01/2021)
2.	Ma, Chengquan: 1 article (01/2021)
3.	Su, Hao: 1 article (01/2021)
4.	Xiong, Jian: 1 article (01/2021)

Related Diseases

1.	Seizures (Absence Seizure) 04/01/1990 - "Phensuximide (PSX) is a 2-arylsuccinimide useful in the treatment of absence seizures. " 06/01/1990 - "Phensuximide (PSX), methsuximide (MSX) and ethosuximide (ESX) are succinimide antiepileptic agents used worldwide in the treatment of absence seizures. " 06/01/1979 - "Phenytoin, carbamazepine, phenobarbital, primidone, phensuximide, methsuximide, alpha-methyl-alpha-phenylsuccinimide, and high concentrations of clonazepam are anticonvulsant drugs that preferentially prevent maximal electroshock seizures (MES) and generalized tonic-clonic convulsions; all these agents inhibit veratridine-induced accumulation of both cyclic AMP and cyclic GMP. "
2.	Absence Epilepsy (Childhood Absence Epilepsy) 10/01/1986 - "Phensuximide is a succinimide antiepileptic drug useful in the treatment of petit mal epilepsy. "
3.	Adrenocortical Carcinoma 01/01/2021 - "Three most small molecules were identified (H-9, AZ-628 and phensuximide) as potential therapeutic drugs for adrenal cortical carcinoma. "
4.	Proteinuria 10/01/1986 - "In the Fischer 344 rat, subacute phensuximide administration (0.3 or 0.6 mmol/kg/day, ip) resulted in transient hematuria and proteinuria, but no change in the other renal function parameters studied. " 10/01/1986 - "Single administration of phensuximide (1.25 mmol/kg, ip) induced mild changes in renal function (trace hematuria, increased proteinuria and decreased p-aminohippurate uptake). "
5.	Hematuria 10/01/1986 - "In the Fischer 344 rat, subacute phensuximide administration (0.3 or 0.6 mmol/kg/day, ip) resulted in transient hematuria and proteinuria, but no change in the other renal function parameters studied. " 10/01/1986 - "Single administration of phensuximide (1.25 mmol/kg, ip) induced mild changes in renal function (trace hematuria, increased proteinuria and decreased p-aminohippurate uptake). "

Related Drugs and Biologics

1.	Anticonvulsants (Antiepileptic Drugs)
2.	succinimide
3.	Phenobarbital (Luminal)
4.	methsuximide (mesuximide)
5.	Veratridine
6.	Primidone (Sertan)
7.	Phenytoin (Dilantin)
8.	p-Aminohippuric Acid (p-Aminohippurate)
9.	Cyclic GMP
10.	Ethosuximide (Zarontin)