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ormetoprim

proposed chemotherapeutic agent; minor descriptor (75-84); on-line & Index Medicus search PYRIMIDINES (75-84)

Also Known As:

2,4-diamino-5-(6-methylveratryl)pyrimidine

Networked: 13 relevant articles (5 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrimidines: 510
    - ormetoprim: 13

Experts

1.	Clauss, Tonya M: 1 article (09/2016)
2.	Field, Cara L: 1 article (09/2016)
3.	Hoopes, Lisa A: 1 article (09/2016)
4.	McDermott, Alexa J: 1 article (09/2016)
5.	Done, Hansa Y: 1 article (01/2015)
6.	Halden, Rolf U: 1 article (01/2015)
7.	Brodbelt, David C: 1 article (08/2012)
8.	Forsythe, Peter J: 1 article (08/2012)
9.	Hendricks, Anke: 1 article (08/2012)
10.	Loeffler, Anette: 1 article (08/2012)

Related Diseases

1.	Infections 09/01/1985 - "In experiment 2, treatment with a combination of 55 mg of sulfadimethoxine/kg of BW and 11 mg of ormetoprim/kg of BW for 23 days was 99.8% effective against Isospora spp infections in dogs. " 03/01/1986 - "The preventive effect of sulfamonomethoxine (Smm) and ormetoprim (Omp) medicated in combination against leucocytozoon infection in chickens was tested in field trials. " 03/01/1986 - "[Effect of sulfamonomethoxine and ormetoprim on leucocytozoon infection in chickens]." 09/01/2016 - "Amikacin and sulfadimethoxine-ormetoprim were administered for suspected bacterial and coccidial infections, respectively. "
2.	Body Weight (Weight, Body) 09/01/1985 - "In experiment 1, daily treatment for 13 to 23 days with a combination of 27.5 mg of sulfadimethoxine/kg of body weight (BW) and 5.5 mg of ormetoprim/kg of BW admixed to the feed resulted in no significant (P greater than 0.05) difference in fecal oocyst counts between treated and nontreated groups of dogs or coyotes. " 03/01/1987 - "The pharmacokinetics, bioavailability, and distribution to the tears of ormetoprim (OMP; 5.5 mg/kg of body weight) and sulfadimethoxine (SDM; 27.5 mg/kg of body weight) were determined following IV or oral administration to 6 Holstein steers. " 02/01/1987 - "The combination of sulfadimethoxine and ormetoprim plus lasalocid significantly (P less than .01) improved weight gain and final body weight, but the length of time that sulfadimethoxine and ormetoprim were fed did not have any effect. "
3.	Coccidiosis 09/01/1985 - "Sulfadimethoxine-ormetoprim combination was evaluated as a coccidiostat against experimentally induced coccidiosis in young dogs and coyotes (Canis latrans). " 09/01/1985 - "Prevention of coccidiosis in domestic dogs and captive coyotes (Canis latrans) with sulfadimethoxine-ormetoprim combination." 10/01/1990 - "Rofenaid (a 5:3 mixture of sulfadimethoxine and ormetoprim) was effective in preventing coccidiosis of chukar partridges. " 10/01/1990 - "Prevention of coccidiosis in the chukar partridge (Alectoris chukar) by medication with sulfadimethoxine and ormetoprim (Rofenaid)."
4.	Weight Gain 02/01/1987 - "The combination of sulfadimethoxine and ormetoprim plus lasalocid significantly (P less than .01) improved weight gain and final body weight, but the length of time that sulfadimethoxine and ormetoprim were fed did not have any effect. " 02/01/1987 - "We studied the effect of sulfadiomethoxine and ormetoprim (Rofenaid 40) in combination with lasalocid (Avatec) and monensin (Coban) on mortality, weight gain, and feed conversion of 2592 male broilers to 47 days of age. "
5.	Pyoderma 08/01/2012 - "A fair level of evidence was identified for moderate to high efficacy of oral amoxicillin-clavulanic acid, clindamycin, cefadroxil, trimethoprim-sulphamethoxazole and sulfadimethoxine-ormetoprim in superficial pyoderma and oral pradofloxacin, oral cefadroxil and subcutaneously injected cefovecin in deep pyoderma. "

Related Drugs and Biologics

1.	Sulfadimethoxine
2.	SDM
3.	sulfadimethoxine drug combination ormetoprim
4.	Amoxicillin-Potassium Clavulanate Combination (Co-amoxiclav)
5.	Trimethoprim (Proloprim)
6.	Sulfamethoxazole
7.	Lasalocid
8.	Clindamycin (Cleocin)
9.	Cefadroxil (Duricef)
10.	cefovecin

Related Therapies and Procedures

1.	Oral Administration