hexestrol bis(diethylaminoethyl ether)

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7 relevant articles (0 outcomes, 0 trials/studies) found for this Bio-Agent

Description: minor descriptor (75-84); on-line & Index Medicus search HEXESTROL/AA (75-84); RN given refers to parent cpd without isomeric designation

Also Known As:

2,2'''-((1,2-diethylethylene)bis(p-phenyleneoxy))-bis(triethylamine); 4,4'-bis(beta-diethylaminoethoxy)alpha,beta-diethyldiphenylethane; Coralgil; Coralgina; Trimanyl; bis(beta-diethylaminoethylether)hexestrol; diethylaminoethoxyhexestrol; hexestrol bis(diethylaminoethyl ether) dihydrochloride; hexestrol bis(diethylaminoethyl ether), (R*,S*)-isomer

Bio-Agent Context: Research Results

Organic Chemicals: 40

Hydrocarbons: 382

Cyclic Hydrocarbons: 2

Aromatic Hydrocarbons: 115

Benzene Derivatives: 9

Benzylidene Compounds

Stilbenes: 39

Diethylstilbestrol: 1257

Hexestrol: 27

hexestrol bis(diethylaminoethyl ether): 7

Related Diseases

1.	Lipidoses 03/01/1987 - "Diethylaminoethoxyhexestrol caused a foam cell lipidosis in humans characterized by phospholipid storage in the liver, spleen, and other tissues, and this represents the first description of acquired lipidosis caused by a drug" 07/01/1974 - "Unusual lipidosis caused by diethylaminoethoxyhexestrol (DH)]" 11/01/1971 - "Specific lipoidosis caused by DH(diethylaminoethoxyhexestrol)-biochemical and pathological changes]" 05/15/1979 - "Chloroquine induced large cytoplasmic vacuoles, whereas the other drugs (quinacrine, 4,4'-diethylaminoethoxyhexestrol, chlorphentermine, iprindole, 1-chloro-amitriptyline, clomipramine) caused formation of lamellated or crystalloid inclusions as usually seen in drug-induced lipidosis" Get all the results and reference details, order at left...
2.	Hypertriglyceridemia 01/09/1985 - "Diethylaminoethoxyhexestrol causes hypertriglyceridemia in guinea pigs." 01/09/1985 - "It is hypothesized that diethylaminoethoxyhexestrol causes hypertriglyceridemia in guinea pigs because these animals are known to have low levels of serum activator for lipoprotein lipase and may be unusually susceptible to agents that inhibit lipoprotein lipase activity" Get all the results and reference details, order at left...
3.	Liver Diseases (Liver Disease) 11/01/1971 - "Case of liver disease caused by DH(diethylaminoethoxyhexestrol)]" Get all the results and reference details, order at left...
4.	Fatty Liver 03/01/1987 - "Metabolic basis of diethylaminoethoxyhexestrol-induced phospholipid fatty liver." 03/01/1987 - "In phospholipid fatty liver, phospholipid accumulation in lysosomes appears to be caused by the presence of diethylaminoethoxyhexestrol in lysosomes at concentrations estimated to be 7.9-20 mM, because drug levels above 1 mM completely block the activity of purified lysosomal phospholipase A1 in vitro." 03/01/1987 - "It has been proposed that diethylaminoethoxyhexestrol causes phospholipid fatty liver by concentrating in lysosomes and inhibiting phospholipases but it has not previously been possible to measure the intralysosomal concentration of diethylaminoethoxyhexestrol" Get all the results and reference details, order at left...
5.	Arteriosclerosis 08/01/1967 - "Effect of trimanyl on lipid metabolism, hemodynamics and coronary blood flow in patients with arteriosclerosis of the coronary vessels]" Get all the results and reference details, order at left...
5 Diseases and 7 more articles analyzed in the Research Interface, order at left...

Related Drugs and Biologics

1.	Phospholipases A1 (Phospholipase A1)
2.	Quinacrine (Mepacrine)
3.	Phospholipases (Phospholipase)
4.	Lipoprotein Lipase (Diacylglycerol Lipase)
5.	Iprindole
6.	Clomipramine (Anafranil)
7.	Chlorphentermine (Chlorphentermine Hydrochloride)
8.	Chloroquine (Aralen)
9.	Amitriptyline (Elavil)
10.	crystalloid solutions
10 Drugs and Important Bio-Agents and 3 more articles analyzed in the Research Interface, order at left...

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