hyaluronate lyase (spreading factor)

11/01/2005 - "A novel bacterial mucinase, glycosulfatase, is associated with bacterial vaginosis."
11/01/2002 - "Application of a novel human cervical mucin-based assay demonstrates the absence of increased mucinase activity in bacterial vaginosis."
04/01/1994 - "Sialidase activity was associated with bacterial vaginosis-linked organisms (Gardnerella vaginalis, Mobiluncus spp, and Mycoplasma hominis) and Chlamydia trachomatis and yeast species; mucinase activity was associated only with bacterial vaginosis-linked microorganisms. "
04/01/1994 - "Mucinase and sialidase activities were more commonly identified, and they occurred in higher concentrations, if present, in women with bacterial vaginosis (mucinase: 44.3% with bacterial vaginosis vs 27.4% without, p = 0.007; sialidase: 45% with bacterial vaginosis vs 12% without p < 0.001). "
04/01/1994 - "Clindamycin, 2% cream, was effective treatment for bacterial vaginosis and temporarily reduced mucinase and sialidase activities. "

11/01/2003 - "Our study shows that supplementation of fenugreek seeds in the diet inhibits colon carcinogenesis, by modulating the activities of beta-glucuronidase and mucinase. "
11/01/2003 - "The effect of fenugreek seeds on the activities of beta-glucuronidase and mucinase during 1,2-dimethylhydrazine (DMH)-induced colon carcinogenesis in rats was studied. "
03/01/2007 - "On luteolin administration, colon cancer incidence, number of tumors per rat and the activities of beta-glucuronidase and mucinase, were significantly decreased both in the initiation and post-initiation stages of colon carcinogenesis dependent on the three different doses given. "
02/09/2011 - "The aim of this study was to determine effects of konjac glucomannan (KGM) in a high fat corn oil diet on risk factors of colon carcinogenesis, that is, fecal β-glucuronidase, mucinase, and bile acids, and on preventive factors, that is, fecal microflora and cecal short-chain fatty acids (SCFAs). "
03/01/2007 - "The aim of the present study was to unravel the chemopreventive effect of luteolin on bacterial enzymes such as beta-glucuronidase and mucinase in a colon carcinogenesis model induced by 1, 2-dimethyl hydrazine (DMH). "

02/01/2011 - "Our results indicate that TagA is a mucinase and suggest that TagA may directly modify host cell surface molecules during V. cholerae infection."
02/01/2009 - "Our data suggest that the StcE mucinase can play an immunomodulatory role by directly altering neutrophil function during infection. "
07/01/1953 - "[Significance of spreading factor in the phenomenon of infection and immunity]."
07/01/1943 - "It is probable that the spread of the virus produced by the bacteria is only partly responsible for the development of the complex infection and that products of these organisms other than the spreading factor play a large part in the mortality of embryos receiving the combination of virus and bacterium."
01/01/1957 - "[Effects of spreading factor on the infection titer of Lansing type poliomyelitis virus]."

05/01/1949 - "Relation of the hemolytic streptococcus to rheumatic fever; effect of streptococcic spreading factor in rheumatic patients and others."
05/26/1954 - "[Biological study of five cases of acute articular rheumatism treated with corticotrophin and cortisone; evaluation of the urinary corticoids and of the skin spreading factor]."

09/05/2013 - "Catalytic mechanism of hyaluronate lyase from Streptococcus pneumonia [corrected] : quantum mechanical/molecular mechanical and density functional theory studies."
09/05/2013 - "Finally, in combination of our previous molecular dynamics simulations, a complete catalytic cycle for the degradation of hyaluronan tetrasaccharide catalyzed by the hyaluronate lyase from Spectrococcus pneumonia is proposed. "
09/05/2013 - "Hyaluronate lyase from Spectrococcus pneumonia can degrade hyaluronic acid, which is one of the major components in the extracellular matrix. "
09/13/2012 - "Hyaluronate lyase from Spectrococcus pneumonia can degrade hyaluronic acid, which is one of the major components in the extracellular matrix. "