|1.||Erne, Paul: 14 articles (10/2015 - 10/2002)|
|2.||Philippova, Maria: 13 articles (10/2015 - 10/2002)|
|3.||Resink, Therese J: 10 articles (10/2015 - 10/2002)|
|4.||Pfaff, Dennis: 8 articles (10/2015 - 12/2011)|
|5.||Kyriakakis, Emmanouil: 7 articles (02/2015 - 12/2008)|
|6.||Takeuchi, Tamotsu: 7 articles (02/2010 - 06/2002)|
|7.||Joshi, Manjunath B: 6 articles (09/2014 - 09/2007)|
|8.||Ohtsuki, Yuji: 6 articles (01/2009 - 06/2002)|
|9.||Maslova, Kseniya: 5 articles (02/2015 - 12/2011)|
|10.||Ranscht, Barbara: 5 articles (08/2013 - 03/2008)|
01/01/2015 - "Since tumor progression is highly dependent upon cell migration and invasion, the aim of the present study was to elucidate the mechanisms of T-cadherin participation in these processes. "
06/01/2004 - "However, few studies have directly tested the hypothesis that H-cadherin, a tailless cadherin, is actually a tumor suppressor, and no published studies have addressed the question of how H-cadherin suppresses cellular transformation. "
08/01/2015 - "T-cadherin has been identified as a tumor-suppressor gene in several types of cancer. "
02/01/2015 - "Compared with the T-cadherin-positive group (55.07, 28.99, and 13.4 %, respectively; P = 0.030, P = 0.0132, and P = 0.009), tumor size >2 cm, lymph-vascular invasion, and pathological stage III disease were seen more frequently in the T-cadherin-negative group (72.60, 49.32, and 31.51 %, respectively). "
01/01/2015 - "T-cadherin hypermethylation, which induces the inactivation of T-cadherin gene, plays an important role in the carcinogenesis, cancer progression, as well as clinical outcome."
|2.||Breast Neoplasms (Breast Cancer)
02/01/2015 - "The purpose of this study was to investigate the correlation of T-cadherin expression with clinicopathological features and prognosis in patients with axillary lymph node-positive breast cancer. "
07/01/1996 - "These studies indicate that downregulation of H-cadherin may be frequent in the breast malignant progression and suggest that it may have prognostic value as a marker for breast cancer development."
02/01/2015 - "Our results suggested that negative T-cadherin expression has a worse prognosis in patients with axillary lymph node-positive breast cancer. "
02/01/2015 - "Based on the immunohistochemistry results, all 142 patients with operable axillary lymph node-positive breast cancer were divided into the T-cadherin-negative and T-cadherin-positive groups. "
02/01/2015 - "T-cadherin association with clinicopathological features and prognosis in axillary lymph node-positive breast cancer."
|3.||Melanoma (Melanoma, Malignant)
12/01/2012 - "The study has identified CDH13 as a novel direct BRN2 transcriptional target gene and has advanced knowledge of mechanisms underlying loss of T-cadherin expression in melanoma."
06/01/2009 - "Our study presents for the first time the down-regulation of H-cadherin in malignant melanomas and its possible functional relevance in maintenance healthy skin architecture."
01/01/2015 - "Thus, T-cadherin plays a dual role in melanoma growth and progression: T-cadherin expression results in anti-angiogenic effects in melanoma, however, this also stimulates transcription of genes responsible for migration and invasion of melanoma cells. "
08/01/2014 - "Notably, we found that the restoration of T-cadherin in melanoma cells causes sensitization to apoptosis induced by CD95/Fas antibody CH-11."
08/01/2014 - "However, detailed knowledge about the consequences of the loss of T-cadherin in melanoma is currently lacking. "
01/01/2015 - "In order to explore the association between cadherin 13 (CDH13) gene promoter methylation and lung carcinoma (LC) risk, we carried out a meta-analysis with searching of PubMed, Web of Science. "
12/01/2012 - "However, they do not account for loss of T-cadherin expression in all carcinomas, and other genetic or epigenetic alterations can be presumed. "
06/01/2012 - "Our results also suggest that demethylation of the T-cadherin gene may be a potential therapeutic strategy for colon carcinoma."
06/01/2012 - "Our findings demonstrate that 5' CpG island methylation is common in colon carcinoma and may play an important role in the inaction of T-cadherin. "
06/01/2012 - "Correlation between T-cadherin gene expression and aberrant methylation of T-cadherin promoter in human colon carcinoma cells."
|5.||Squamous Cell Carcinoma (Epidermoid Carcinoma)
05/01/2013 - "T-cadherin is gaining recognition as a determinant for the development of incipient invasive squamous cell carcinoma (SCC). "
09/01/2012 - "T-Cadherin is an auxiliary negative regulator of EGFR pathway activity in cutaneous squamous cell carcinoma: impact on cell motility."
08/01/2010 - "T-cadherin loss induces an invasive phenotype in human keratinocytes and squamous cell carcinoma (SCC) cells in vitro and is associated with malignant transformation of cutaneous SCC in vivo."
06/01/2007 - "We previously reported that T-cadherin is normally expressed on the basal keratinocytes of the epidermis and is down-regulated in cutaneous squamous cell carcinoma (SCC). "
04/01/2005 - "T-cadherin negatively regulates the proliferation of cutaneous squamous carcinoma cells."
|3.||Messenger RNA (mRNA)
|5.||Epidermal Growth Factor (EGF)
|6.||Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
|8.||Choline (Choline Chloride)
|2.||Heterologous Transplantation (Xenotransplantation)
|3.||Transplantation (Transplant Recipients)