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ATI 2001

structure given in first source

Also Known As:

3-((4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl)carbonyl)-2-benzofuranylacetate methyl ester; ATI-2001

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzofurans: 26
      - Amiodarone: 5571
        ATI 2001: 2

Experts

1.	Dennis, D M: 1 article (11/2000)
2.	Druzgala, P: 1 article (11/2000)
3.	Gonzalez, M D: 1 article (11/2000)
4.	Milner, P: 1 article (11/2000)
5.	Morey, T E: 1 article (11/2000)
6.	Raatikainen, M J: 1 article (11/2000)

Related Diseases

1.	Ventricular Tachycardia 06/01/1996 - "The lack of reverse frequency-dependent effects on ventricular repolarization and refractoriness suggests that ATI-2001 may be more efficacious than d-sotalol or other pure class III drugs in treating ventricular tachycardias and less likely to become proarrhythmic at normal or slow heart rates."
2.	Supraventricular Tachycardia 11/01/2000 - "Given these data, ATI-2001 should not only be useful for terminating ongoing and preventing reoccurrence of atrial tachyarrhythmias but also to treat supraventricular tachycardias involving the AV node and to control ventricular rate during atrial tachyarrhythmias. "
3.	Tachycardia (Tachyarrhythmias) 11/01/2000 - "Given these data, ATI-2001 should not only be useful for terminating ongoing and preventing reoccurrence of atrial tachyarrhythmias but also to treat supraventricular tachycardias involving the AV node and to control ventricular rate during atrial tachyarrhythmias. " 11/01/2000 - "We recently demonstrated that the short-acting analog of amiodarone, ATI-2001, caused favorable effects in guinea pig ventricular myocardium on electrophysiological substrates underlying tachyarrhythmia initiation, perpetuation, and termination. " 11/01/2000 - "Whether the observed differences in the pharmacokinetic properties render ATI-2001 superior to amiodarone in acute tachyarrhythmia management and less likely to accumulate into tissues during chronic therapy remains to be established."

Related Drugs and Biologics

1.	Sotalol (Sotalol Hydrochloride)
2.	Amiodarone (Amiodarona)

Related Therapies and Procedures

1.	Therapeutics