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N-carbamylmethoxypoly(ethylene glycol)- 1,2- distearoyl- sn- glycero- 3- phosphoethanolamine

improves liposome in vivo circulation time

Also Known As:

MPEG(1900)-DSPE; MPEG(2000)-DSPE; N-carbamylmethoxypoly(ethylene glycol)-1,2-distearoyl-sn-glycero-3-phosphoethanolamine sodium salt

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Lipids: 114793
- Membrane Lipids: 1591
  - Phospholipids: 11903
    - Glycerophosphates: 118
      - Phosphatidic Acids: 358
        Glycerophospholipids: 689
        Phosphatidylethanolamines: 167
        N-carbamylmethoxypoly(ethylene glycol)-1,2-distearoyl-sn-glycero-3-phosphoethanolamine: 1
Organic Chemicals: 133
- Alcohols: 595
  - Glycols: 38
    - Ethylene Glycols: 8
      - Polyethylene Glycols: 3865
        N-carbamylmethoxypoly(ethylene glycol)-1,2-distearoyl-sn-glycero-3-phosphoethanolamine: 1
Macromolecular Substances: 97
- Polymers: 13051
  - Polyethylene Glycols: 3865
    - N-carbamylmethoxypoly(ethylene glycol)-1,2-distearoyl-sn-glycero-3-phosphoethanolamine: 1
Biomedical and Dental Materials
- Polymers: 13051
  - Polyethylene Glycols: 3865
    - N-carbamylmethoxypoly(ethylene glycol)-1,2-distearoyl-sn-glycero-3-phosphoethanolamine: 1
Technology, Industry, and Agriculture
- Manufactured Materials
  - Biomedical and Dental Materials
    - Polymers: 13051
      - Polyethylene Glycols: 3865
        N-carbamylmethoxypoly(ethylene glycol)-1,2-distearoyl-sn-glycero-3-phosphoethanolamine: 1

Experts

1.	Allen, Theresa M: 1 article (01/2003)
2.	Boch, Ron: 1 article (01/2003)
3.	Boey, Anthony: 1 article (01/2003)
4.	Hansen, Christian B: 1 article (01/2003)
5.	Zhang, Janny X: 1 article (01/2003)

Related Diseases

1.

Neoplasms (Cancer)

01/17/2003 - "mPEG(2000)-DSPE micellar formulations also showed tumor control when administered by a single intratumoral injection followed by light irradiation to the tumor within 45-60 min after drug administration. "
01/17/2003 - "In vivo, the A-ring benzoporphyrin, verteporfin, had higher levels of delivery and greater tumor control in mice than the B-ring derivative when formulated in mPEG(2000)-DSPE micelles and administered intravenously. "

Related Drugs and Biologics

1.	Micelles
2.	Verteporfin (Visudyne)