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polycystic kidney disease 2 protein

amino acid sequence in first source
Also Known As:
PC2 polycystin-2, human; PKD2 protein, human; PKD2 protein, rat; PKD4 protein, human; Pkd2 protein, mouse; TRPP2 protein, mouse; autosomal dominant polycystic kidney disease type II protein; polycystic kidney disease 2 (autosomal dominant) protein, human; polycystic kidney disease 2 protein, mouse; polycystin 2; polycystin-2, human; polycystin-2, mouse
Networked: 25 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Audrézet, Marie-Pierre: 2 articles (12/2014 - 09/2011)
2. Keeler, Camille: 2 articles (05/2014 - 12/2013)
3. Ehrlich, Barbara E: 2 articles (05/2014 - 12/2013)
4. Hodsdon, Michael E: 2 articles (05/2014 - 12/2013)
5. Kuo, Ivana Y: 2 articles (05/2014 - 12/2013)
6. Menè, Paolo: 2 articles (01/2013 - 01/2006)
7. Zhou, Jing: 2 articles (10/2010 - 04/2003)
8. Li, Xiaogang: 2 articles (04/2010 - 04/2003)
9. Ward, Christopher J: 2 articles (02/2009 - 03/2004)
10. Harris, Peter C: 2 articles (02/2009 - 03/2004)

Related Diseases

1. Polycystic Kidney Diseases (Polycystic Kidney Disease)
12/01/2014 - "Here, we provide a comprehensive review of these significant advances as well as those related to disease pathogenesis models, including mutation analysis of PKD1 and PKD2 (encoding polycystin 2), current mutation detection rate, allelic heterogeneity, genotype and phenotype relationships (in terms of three different inheritance patterns: classical autosomal dominant inheritance, complex inheritance, and somatic and germline mosaicism), modifier genes, the role of second somatic mutation hit in renal cystogenesis, and findings from mouse models of polycystic kidney disease. "
12/17/2013 - "Finally, we simulate and compare experimental data fits for the binding isotherms of Ca(2+) binding to its canonical binding site (EF-hand domain) of polycystin 2, a Ca(2+)-dependent channel with relevance to polycystic kidney disease. "
05/01/2011 - "Tying TAZ and Nek1 into polycystic kidney disease through polycystin 2 levels."
04/01/2007 - "The zebrafish mutation curly up (cup) affects the zebrafish ortholog of polycystic kidney disease 2, a gene that encodes the Ca(2+)-activated non-specific cation channel, Polycystin 2. We have characterized two alleles of cup, both of which display defects in organ positioning that resemble human heterotaxia, as well as abnormalities in asymmetric gene expression in the lateral plate mesoderm (LPM) and dorsal diencephalon of the brain. "
03/01/1998 - "Immunohistochemical studies have shown that polycystin 1 and polycystin 2 are developmentally regulated and are overexpressed in polycystic kidneys. "
2. Autosomal Dominant Polycystic Kidney (ADPKD)
3. Cysts
4. Cystic Kidney Diseases (Cystic Kidney Disease)
5. Autosomal Recessive Polycystic Kidney (Polycystic Kidney Disease, Infantile, Type I)

Related Drugs and Biologics

1. polycystic kidney disease 1 protein
2. Proteins (Proteins, Gene)
3. Calcium
4. beta Catenin
5. Small Interfering RNA (siRNA)
6. Cadherins (E-Cadherin)
7. Calcium Channels (Calcium Channel)
8. Staphylococcal Protein A (A, Protein)
9. Immune Sera (Antisera)