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falcipain
7
relevant articles (0 outcomes,
0 trials/studies)
found for this Bio-Agent
Description: a Plasmodium falciparum trophozoite cysteine proteinase that degrades hemoglobin; a target for antimalarial chemotherapy
Also Known As:28-kDa malarial cysteine proteinase; malarial hemoglobinase, 28-kDa
Bio-Agent Context: Research Results
Experts
| 1. | Singh, Ajay: 1 article (08/2004) |
| 2. | Rosenthal, Philip J: 1 article (08/2004) |
| 3. | Holder, Anthony A: 1 article (12/2002) |
| 4. | Bozdech, Zbynek: 1 article (12/2002) |
| 5. | Baruch, Amos: 1 article (12/2002) |
| 6. | Medzihradszky, Katlin F: 1 article (12/2002) |
| 7. | Engel, Juan: 1 article (12/2002) |
| 8. | Greenbaum, Doron C: 1 article (12/2002) |
| 9. | Bogyo, Matthew: 1 article (12/2002) |
| 10. | Grainger, Munira: 1 article (12/2002) |
Related Diseases
| 1. | Malaria
03/01/2007
- "E64d reduced the level of oocyst production more effectively than that reported previously for falcipain 1-knockout parasites, suggesting that falcipains 2 and 3 may also be involved in malaria parasite transmission"
06/01/2006 - "We present here one such optimized inhibitor that showed selective inhibition of falcipain 1, a protease of the malaria-causing parasite, Plasmodium falciparum." 11/04/2005 - "Treatment of malaria parasites with either of the falcipain siRNAs considerably reduced parasite growth" 12/06/2002 - "A role for the protease falcipain 1 in host cell invasion by the human malaria parasite." 04/01/1999 - "We now report an evaluation of orally administered peptidyl inhibitors of falcipain in a mouse malaria model" Get all the results and reference details, order at left... |
| 1 Diseases and 7 more articles analyzed in the Research Interface, order at left... | |
Related Drugs and Biologics
| 1. | Cysteine Endopeptidases (Cysteine Proteases)
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| 2. | Hemoglobins (Hemoglobin)
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| 3. | Antimalarials (Antimalarial Agents)
|
| 4. | falcipain 3
|
| 5. | falcipain 2
|
| 5 Drugs and Important Bio-Agents and 3 more articles analyzed in the Research Interface, order at left... | |
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